The impact of oral cryotherapy and oral and gastrointestinal mucositis after autologous stem cell transplantation
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10218385" target="_blank" >RIV/00216208:11140/14:10218385 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00669806:_____/14:10218385
Výsledek na webu
<a href="http://www.sciencedirect.com/science/article/pii/S1462388913001531" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1462388913001531</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ejon.2013.11.001" target="_blank" >10.1016/j.ejon.2013.11.001</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The impact of oral cryotherapy and oral and gastrointestinal mucositis after autologous stem cell transplantation
Popis výsledku v původním jazyce
Oral mucositis (OM) is a post-transplant complication. Oral cavity cooling (cryotherapy) provided during high-dose melphalan short infusion reduces the incidence of OM. We compared patients with (n=135) and without OM (n=110) after high-dose chemotherapyand autologous stem cells transplantation. We observed OM, gastrointestinal mucositis (GIM) and the impact of cryotherapy. The incidence of OM was significantly lower in the cryotherapy group. The incidence OM and GIM were more common in females and BEAM-conditioned patients. The incidence of fevers and use of IV antibiotics was most dependent on OM and GIM, and reduced oral tissue damage (OM) mediated by oral cryotherapy did not appear to lead to reductions in FUO and antibiotic use. Although our findings do suggest that OM may have less of an impact on FUO and antibiotic use compared to GIM, we do not underestimate the importance of oral cooling in high-dose melphalan patients.
Název v anglickém jazyce
The impact of oral cryotherapy and oral and gastrointestinal mucositis after autologous stem cell transplantation
Popis výsledku anglicky
Oral mucositis (OM) is a post-transplant complication. Oral cavity cooling (cryotherapy) provided during high-dose melphalan short infusion reduces the incidence of OM. We compared patients with (n=135) and without OM (n=110) after high-dose chemotherapyand autologous stem cells transplantation. We observed OM, gastrointestinal mucositis (GIM) and the impact of cryotherapy. The incidence of OM was significantly lower in the cryotherapy group. The incidence OM and GIM were more common in females and BEAM-conditioned patients. The incidence of fevers and use of IV antibiotics was most dependent on OM and GIM, and reduced oral tissue damage (OM) mediated by oral cryotherapy did not appear to lead to reductions in FUO and antibiotic use. Although our findings do suggest that OM may have less of an impact on FUO and antibiotic use compared to GIM, we do not underestimate the importance of oral cooling in high-dose melphalan patients.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FD - Onkologie a hematologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
European Journal of Oncology Nursing
ISSN
1462-3889
e-ISSN
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Svazek periodika
18
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
2
Strana od-do
228-229
Kód UT WoS článku
000333859800015
EID výsledku v databázi Scopus
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