Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in vitro

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10312227" target="_blank" >RIV/00216208:11140/15:10312227 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/15:00453672 RIV/60460709:41210/15:67166 RIV/00027014:_____/15:N0000001

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.niox.2015.09.007" target="_blank" >http://dx.doi.org/10.1016/j.niox.2015.09.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.niox.2015.09.007" target="_blank" >10.1016/j.niox.2015.09.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in vitro

Popis výsledku v původním jazyce

Hydrogen sulfide, one of three known gasotransmitters, is involved in physiological processes, including reproductive functions. Oocyte maturation and surrounding cumulus cell expansion play an essential role in female reproduction and subsequent embryonic development. Although the positive effects of exogenous hydrogen sulfide on maturing oocytes are well known, the role of endogenous hydrogen sulfide, which is physiologically released by enzymes, has not yet been described in oocytes. In this study, we observed the presence of Cystathionine ?-Synthase (CBS), Cystathionine ?-Lyase (CTH) and 3-Mercaptopyruvate Sulfurtransferase (3-MPST), hydrogen sulfide-releasing enzymes, in porcine oocytes. Endogenous hydrogen sulfide production was detected in immature and matured oocytes as well as its requirement for meiotic maturation. Individual hydrogen sulfide-releasing enzymes seem to be capable of substituting for each other in hydrogen sulfide production. However, meiosis suppression by inh

Název v anglickém jazyce

Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in vitro

Popis výsledku anglicky

Hydrogen sulfide, one of three known gasotransmitters, is involved in physiological processes, including reproductive functions. Oocyte maturation and surrounding cumulus cell expansion play an essential role in female reproduction and subsequent embryonic development. Although the positive effects of exogenous hydrogen sulfide on maturing oocytes are well known, the role of endogenous hydrogen sulfide, which is physiologically released by enzymes, has not yet been described in oocytes. In this study, we observed the presence of Cystathionine ?-Synthase (CBS), Cystathionine ?-Lyase (CTH) and 3-Mercaptopyruvate Sulfurtransferase (3-MPST), hydrogen sulfide-releasing enzymes, in porcine oocytes. Endogenous hydrogen sulfide production was detected in immature and matured oocytes as well as its requirement for meiotic maturation. Individual hydrogen sulfide-releasing enzymes seem to be capable of substituting for each other in hydrogen sulfide production. However, meiosis suppression by inh

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nitric Oxide - Biology and Chemistry

ISSN

1089-8603

e-ISSN

—

Svazek periodika

51

Číslo periodika v rámci svazku

October

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

24-35

Kód UT WoS článku

000366065100004

EID výsledku v databázi Scopus

2-s2.0-84944755165