Mammary analog secretory carcinoma of minor palatal salivary glands: A case report and review of the literature

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10323758" target="_blank" >RIV/00216208:11140/15:10323758 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ajoms.2015.02.005" target="_blank" >http://dx.doi.org/10.1016/j.ajoms.2015.02.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ajoms.2015.02.005" target="_blank" >10.1016/j.ajoms.2015.02.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mammary analog secretory carcinoma of minor palatal salivary glands: A case report and review of the literature

Popis výsledku v původním jazyce

Mammary analog secretory carcinoma (MASC) is a recently described entity of malignant salivary gland tumors that histologically resembles mammary secretory carcinoma (SC) of the breast. MASC was earlier often categorized as an unusual variant of salivary acinic cell carcinoma (AciCC) or adenoid cystic carcinoma (ADCC). According to the literature, MASC is most often found in the major salivary glands, and it has been suggested to metastasize more often than AciCC. Here, we present the first case of MASC occurring in minor salivary glands of the hard palate, including diagnosis, treatment, and follow-up. Diagnosis was based on histomorphological and immunohistochemical findings and on a specific translocation of the ETV6 gene on chromosome 12p13. Differential diagnosis excluded AciCC, ADCC, cribriform cystadenocarcinoma, and polymorphous low-grade adenocarcinoma. Radiological, resection, and immunohistological findings are presented with radiological and clinical pictures. In our patient, neck dissection was not performed, and during the 18-month follow-up no recurrence or metastasis was found. Despite all the MASC cases described in the literature, standardized treatment protocols are still lacking.

Název v anglickém jazyce

Mammary analog secretory carcinoma of minor palatal salivary glands: A case report and review of the literature

Popis výsledku anglicky

Mammary analog secretory carcinoma (MASC) is a recently described entity of malignant salivary gland tumors that histologically resembles mammary secretory carcinoma (SC) of the breast. MASC was earlier often categorized as an unusual variant of salivary acinic cell carcinoma (AciCC) or adenoid cystic carcinoma (ADCC). According to the literature, MASC is most often found in the major salivary glands, and it has been suggested to metastasize more often than AciCC. Here, we present the first case of MASC occurring in minor salivary glands of the hard palate, including diagnosis, treatment, and follow-up. Diagnosis was based on histomorphological and immunohistochemical findings and on a specific translocation of the ETV6 gene on chromosome 12p13. Differential diagnosis excluded AciCC, ADCC, cribriform cystadenocarcinoma, and polymorphous low-grade adenocarcinoma. Radiological, resection, and immunohistological findings are presented with radiological and clinical pictures. In our patient, neck dissection was not performed, and during the 18-month follow-up no recurrence or metastasis was found. Despite all the MASC cases described in the literature, standardized treatment protocols are still lacking.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

ISSN

2212-5558

e-ISSN

—

Svazek periodika

27

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

698-702

Kód UT WoS článku

000371599000019

EID výsledku v databázi Scopus

2-s2.0-84940573624