Hybrid Epithelioid Schwannoma/Perineurioma
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10324178" target="_blank" >RIV/00216208:11140/16:10324178 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1097/DAD.0000000000000532" target="_blank" >http://dx.doi.org/10.1097/DAD.0000000000000532</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/DAD.0000000000000532" target="_blank" >10.1097/DAD.0000000000000532</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Hybrid Epithelioid Schwannoma/Perineurioma
Popis výsledku v původním jazyce
We report a case of a 58-year-old who woman presented with a solitary slowly growing subcutaneous nodule covered by normally appearing skin on her left groin. Microscopically, the lesion was well circumscribed but unencapsulated, and showed biphasic cellular differentiation. One cell population was presented by small rounded (epithelioid) cells arranged singly, in small aggregates or short cords, whereas the second one was composed of cells with slender nuclei and delicate elongated bipolar cytoplasmic processes. On immunohistochemistry, the epithelioid component showed positive reaction for S-100 protein and negative for epithelial membrane ntigen (EMA), thus compatible with schwannian differentiation and resembling epithelioid schwannoma. The other component showed reverse immunophenotype being S-100 protein negative and EMA ositive, thus corresponding to perineuriomatous differentiation. The linicopathologic nd immunohistochemical features of the lesion were ompatible with hybrid epithelioid schwannoma/perineurioma, a rare orphological variant of peripheral nerve sheath tumors.
Název v anglickém jazyce
Hybrid Epithelioid Schwannoma/Perineurioma
Popis výsledku anglicky
We report a case of a 58-year-old who woman presented with a solitary slowly growing subcutaneous nodule covered by normally appearing skin on her left groin. Microscopically, the lesion was well circumscribed but unencapsulated, and showed biphasic cellular differentiation. One cell population was presented by small rounded (epithelioid) cells arranged singly, in small aggregates or short cords, whereas the second one was composed of cells with slender nuclei and delicate elongated bipolar cytoplasmic processes. On immunohistochemistry, the epithelioid component showed positive reaction for S-100 protein and negative for epithelial membrane ntigen (EMA), thus compatible with schwannian differentiation and resembling epithelioid schwannoma. The other component showed reverse immunophenotype being S-100 protein negative and EMA ositive, thus corresponding to perineuriomatous differentiation. The linicopathologic nd immunohistochemical features of the lesion were ompatible with hybrid epithelioid schwannoma/perineurioma, a rare orphological variant of peripheral nerve sheath tumors.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FP - Ostatní lékařské obory
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
American Journal of Dermatopathology
ISSN
0193-1091
e-ISSN
—
Svazek periodika
38
Číslo periodika v rámci svazku
7
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
3
Strana od-do
"e90"-"e92"
Kód UT WoS článku
000378157800002
EID výsledku v databázi Scopus
2-s2.0-84957823957