The role of silver nanoparticles synthesized from Brassica olerace for determination of Aspirin in pharmaceutical samples by standard additions method

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F23%3A10483273" target="_blank" >RIV/00216208:11140/23:10483273 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=t7WimPahkd" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=t7WimPahkd</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.56053/7.2.95" target="_blank" >10.56053/7.2.95</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The role of silver nanoparticles synthesized from Brassica olerace for determination of Aspirin in pharmaceutical samples by standard additions method

Popis výsledku v původním jazyce

In this study, silver nanoparticles (Ag NPs) were prepared from Brassica oleracea (BO) leaflet extract (BO-AgNPs) and applied for to determination of Aspirin in pharmaceutical samples through selective and sensitive spectrophotometric standard additions method. The measurements of UV-Visible, X-ray diffraction (XRD), Fourier transform infrared (FTIR) and scanning electron microscopy (SEM) have been used to confirm the formation of BO-AgNPs, revealing a prominent absorption band at 450 nm, crystallinity, and an agglomerated morphology having an average particle size of 29 nm. Aspirin in Acifein, Aspirin, Acylpyrin and Disprin tablets was determined through the complexation with BO-AgNPs, revealing a linear range of 1-10 mg/10 mL and limit of detection (LOD) as 0.09, 0.46, 0.69 and 0.99 mg/10 mL, respectively. An average percent recovery for four samples were found to be 90, 99, 101 and 99 % and relative standard deviation (RSD) as 1.6, 0.6, 0.3 and 1.4, respectively. The suggested method was successfully used for the quantitative analysis of pharmaceutical tablets, which opens up the possibility that Ag NPs could be used to determine biological molecules when interferences from real samples are present.

Název v anglickém jazyce

The role of silver nanoparticles synthesized from Brassica olerace for determination of Aspirin in pharmaceutical samples by standard additions method

Popis výsledku anglicky

In this study, silver nanoparticles (Ag NPs) were prepared from Brassica oleracea (BO) leaflet extract (BO-AgNPs) and applied for to determination of Aspirin in pharmaceutical samples through selective and sensitive spectrophotometric standard additions method. The measurements of UV-Visible, X-ray diffraction (XRD), Fourier transform infrared (FTIR) and scanning electron microscopy (SEM) have been used to confirm the formation of BO-AgNPs, revealing a prominent absorption band at 450 nm, crystallinity, and an agglomerated morphology having an average particle size of 29 nm. Aspirin in Acifein, Aspirin, Acylpyrin and Disprin tablets was determined through the complexation with BO-AgNPs, revealing a linear range of 1-10 mg/10 mL and limit of detection (LOD) as 0.09, 0.46, 0.69 and 0.99 mg/10 mL, respectively. An average percent recovery for four samples were found to be 90, 99, 101 and 99 % and relative standard deviation (RSD) as 1.6, 0.6, 0.3 and 1.4, respectively. The suggested method was successfully used for the quantitative analysis of pharmaceutical tablets, which opens up the possibility that Ag NPs could be used to determine biological molecules when interferences from real samples are present.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Experimental and Theoretical Nanotechnology

ISSN

2590-4132

e-ISSN

2590-4132

Svazek periodika

7

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DZ - Alžírská demokratická a lidová republika

Počet stran výsledku

16

Strana od-do

95-110

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85200961355