Spared cognitive processing of visual oddballs despite delayed visual evoked potentials in patient with partial recovery of vision after 53 years of blindness

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F13%3A10138854" target="_blank" >RIV/00216208:11150/13:10138854 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081740:_____/13:00391871

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0042698913000151" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0042698913000151</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.visres.2012.12.013" target="_blank" >10.1016/j.visres.2012.12.013</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spared cognitive processing of visual oddballs despite delayed visual evoked potentials in patient with partial recovery of vision after 53 years of blindness

Popis výsledku v původním jazyce

We examined the visual and cognitive functions of a 72-year-old subject, KP, who recovered his sight after 53 years of visual deprivation. We used visual evoked potentials (VEPs) to pattern-reversal and motion-onset stimuli and cognitive responses (ERPs)during the oddball paradigm to assess the effect of long-term deprivation on a mature visual system. KP lost his sight at the age of 17 years, and light projection onto his right retina was restored at 71 years by a corneal implant. Nine months after sight recovery we recorded reproducible responses to all examined stimuli. The response to pattern reversal contained two P100-like peaks with the later peak being dominant and significantly delayed (260 ms) when compared to the P100s of two control subjects, to whom the stimuli were adjusted in size and contrast to mimic KP's vision. KP's motion-onset VEPs to full-field and peripheral stimuli had a characteristic shape with a well-defined N2 peak; however, both peaks were significantly de

Název v anglickém jazyce

Spared cognitive processing of visual oddballs despite delayed visual evoked potentials in patient with partial recovery of vision after 53 years of blindness

Popis výsledku anglicky

We examined the visual and cognitive functions of a 72-year-old subject, KP, who recovered his sight after 53 years of visual deprivation. We used visual evoked potentials (VEPs) to pattern-reversal and motion-onset stimuli and cognitive responses (ERPs)during the oddball paradigm to assess the effect of long-term deprivation on a mature visual system. KP lost his sight at the age of 17 years, and light projection onto his right retina was restored at 71 years by a corneal implant. Nine months after sight recovery we recorded reproducible responses to all examined stimuli. The response to pattern reversal contained two P100-like peaks with the later peak being dominant and significantly delayed (260 ms) when compared to the P100s of two control subjects, to whom the stimuli were adjusted in size and contrast to mimic KP's vision. KP's motion-onset VEPs to full-field and peripheral stimuli had a characteristic shape with a well-defined N2 peak; however, both peaks were significantly de

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Vision Research

ISSN

0042-6989

e-ISSN

—

Svazek periodika

81

Číslo periodika v rámci svazku

April 5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

1-5

Kód UT WoS článku

000316837900001

EID výsledku v databázi Scopus

—