Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10366356" target="_blank" >RIV/00216208:11150/17:10366356 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00099904 RIV/65269705:_____/17:00068016 RIV/00179906:_____/17:10366356

Výsledek na webu

<a href="http://dx.doi.org/10.1371/journal.pone.0189394" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0189394</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0189394" target="_blank" >10.1371/journal.pone.0189394</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes

Popis výsledku v původním jazyce

The main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by pre-term prelabor rupture of membranes (PPROM) and the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). The second aim was to test WBC diagnostic indices with respect to the presence of MIAC and/or IAI. Four hundred and seventy-nine women with singleton pregnancies complicated by PPROM, between February 2012 and June 2017, were included in this study. Maternal blood and amniotic fluid samples were collected at the time of admission. Maternal WBC count was assessed. Women with MIAC or IAI had higher WBC counts than those without (with MIAC: median, 12.8 x 10(9) /L vs. without MIAC: median, 11.9 x 10(9) /L; p = 0.0006; with IAI: median, 13.7 x 10(9) /L vs. without IAI: median, 11.9 x 10(9)/L; p &lt; 0.0001). The maternal WBC count at the time of admission showed poor diagnostic indices for the identification of the presence of both MIAC and IAI.

Název v anglickém jazyce

Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes

Popis výsledku anglicky

The main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by pre-term prelabor rupture of membranes (PPROM) and the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). The second aim was to test WBC diagnostic indices with respect to the presence of MIAC and/or IAI. Four hundred and seventy-nine women with singleton pregnancies complicated by PPROM, between February 2012 and June 2017, were included in this study. Maternal blood and amniotic fluid samples were collected at the time of admission. Maternal WBC count was assessed. Women with MIAC or IAI had higher WBC counts than those without (with MIAC: median, 12.8 x 10(9) /L vs. without MIAC: median, 11.9 x 10(9) /L; p = 0.0006; with IAI: median, 13.7 x 10(9) /L vs. without IAI: median, 11.9 x 10(9)/L; p &lt; 0.0001). The maternal WBC count at the time of admission showed poor diagnostic indices for the identification of the presence of both MIAC and IAI.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

<a href="/cs/project/NV16-28587A" target="_blank" >NV16-28587A: Neinvazivní detekce intraamniální infekce stanovením dominantní bakterie v cervikální tekutině</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLoS One

ISSN

1932-6203

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

17

Strana od-do

—

Kód UT WoS článku

000417698200039

EID výsledku v databázi Scopus

2-s2.0-85038430733