Dermatitis herpetiformis Duhring - evaluation of disease severity and tissue transglutaminase levels in 122 patients on dapsone therapy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10428511" target="_blank" >RIV/00216208:11150/21:10428511 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/21:10428511 RIV/00216208:11140/21:10428511 RIV/00179906:_____/21:10428511

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=N9M6KclPpy" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=N9M6KclPpy</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/09540105.2021.1918067" target="_blank" >10.1080/09540105.2021.1918067</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Dermatitis herpetiformis Duhring - evaluation of disease severity and tissue transglutaminase levels in 122 patients on dapsone therapy

Popis výsledku v původním jazyce

The aim of our study was to characterize the group of patients suffering from dermatitis herpetiformis Duhring (DH) and to make the statistical analysis of monitored parameters. We retrospectively analysed the data of 122 patients with DH (age, gender, the severity of DH, tissue transglutaminase antibodies IgA (IgA-TGA) level and dapsone dose). The mild form of DH was recorded in 69 patients (56.6%), the moderate form in 48 patients (39.3%) and the severe form in 5 patients (4.1%); 118 patients (96.7%) are on dapsone therapy, 3.2% of patients are only on gluten-free diet. The median of average IgA-TGA in the mild form is 6.25 U/ml, in the moderate form 14.45 U/ml and in the severe form 10.33 U/ml. Although the significant relation of the IgA-TGA to the disease severity was not confirmed, there is some trend in the increase of the IgA-TGA level from mild to moderate and severe form of DH.

Název v anglickém jazyce

Dermatitis herpetiformis Duhring - evaluation of disease severity and tissue transglutaminase levels in 122 patients on dapsone therapy

Popis výsledku anglicky

The aim of our study was to characterize the group of patients suffering from dermatitis herpetiformis Duhring (DH) and to make the statistical analysis of monitored parameters. We retrospectively analysed the data of 122 patients with DH (age, gender, the severity of DH, tissue transglutaminase antibodies IgA (IgA-TGA) level and dapsone dose). The mild form of DH was recorded in 69 patients (56.6%), the moderate form in 48 patients (39.3%) and the severe form in 5 patients (4.1%); 118 patients (96.7%) are on dapsone therapy, 3.2% of patients are only on gluten-free diet. The median of average IgA-TGA in the mild form is 6.25 U/ml, in the moderate form 14.45 U/ml and in the severe form 10.33 U/ml. Although the significant relation of the IgA-TGA to the disease severity was not confirmed, there is some trend in the increase of the IgA-TGA level from mild to moderate and severe form of DH.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30216 - Dermatology and venereal diseases

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Food and Agricultural Immunology

ISSN

0954-0105

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

16

Strana od-do

237-252

Kód UT WoS článku

000655256300001

EID výsledku v databázi Scopus

2-s2.0-85107184009