Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practise

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F22%3A10442115" target="_blank" >RIV/00216208:11150/22:10442115 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/22:10442115

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8e1f9qNK8G" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8e1f9qNK8G</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10072-021-05563-x" target="_blank" >10.1007/s10072-021-05563-x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practise

Popis výsledku v původním jazyce

Autoimmune and limbic encephalitides are still rare diseases characterized by rapid diagnostics and treatment development in recent years. The incidence of anti-N-methyl-D aspartate receptor /NMDAR/ encephalitis in about 1.5 per million person per year, and the incidence of paraneoplastic neurological syndromes /PNS/ including limbic encephalitis /LE/ is about 1.22 per 100 000 person per year (Vogrig et al. J Neurol 267:26-35, 1; Dalmau et al. Ann Neurol 61:25-36, 2). The diagnostic criteria of anti-NMDAR encephalitis are alredy well established (Zuliani et al. Neurol Sci 40:2017-2030, 10). We provide immunological and clinical characteristics of anti-NMDAR encephalitis case series emphasizing unusual association with colon tumour in one case and complete recovery in two cases. Then we report two cases of onconeural and cell surface antibody negative limbic encephalitis /LE/ associated with tumours, seizures, cognitive and behavioural changes resulting in severe cerebellar syndrome and fatal outcome. The clinical characteristics and results of selected paraclinical examinations as electroencephalography /EEG/. magnetic resonance imaging /MRI/ and cerebrospinal fluid /CSF/ analysis are reviewed.

Název v anglickém jazyce

Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practise

Popis výsledku anglicky

Autoimmune and limbic encephalitides are still rare diseases characterized by rapid diagnostics and treatment development in recent years. The incidence of anti-N-methyl-D aspartate receptor /NMDAR/ encephalitis in about 1.5 per million person per year, and the incidence of paraneoplastic neurological syndromes /PNS/ including limbic encephalitis /LE/ is about 1.22 per 100 000 person per year (Vogrig et al. J Neurol 267:26-35, 1; Dalmau et al. Ann Neurol 61:25-36, 2). The diagnostic criteria of anti-NMDAR encephalitis are alredy well established (Zuliani et al. Neurol Sci 40:2017-2030, 10). We provide immunological and clinical characteristics of anti-NMDAR encephalitis case series emphasizing unusual association with colon tumour in one case and complete recovery in two cases. Then we report two cases of onconeural and cell surface antibody negative limbic encephalitis /LE/ associated with tumours, seizures, cognitive and behavioural changes resulting in severe cerebellar syndrome and fatal outcome. The clinical characteristics and results of selected paraclinical examinations as electroencephalography /EEG/. magnetic resonance imaging /MRI/ and cerebrospinal fluid /CSF/ analysis are reviewed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neurological Sciences

ISSN

1590-1874

e-ISSN

1590-3478

Svazek periodika

43

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

4

Strana od-do

687-690

Kód UT WoS článku

000687902800001

EID výsledku v databázi Scopus

2-s2.0-85113315851