New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F12%3A10118797" target="_blank" >RIV/00216208:11160/12:10118797 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.tswj.com/2012/746412/" target="_blank" >http://www.tswj.com/2012/746412/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1100/2012/746412" target="_blank" >10.1100/2012/746412</a>

Jazyk výsledku

angličtina

Název v původním jazyce

New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture

Popis výsledku v původním jazyce

The production of secondary metabolites in Trifolium pratense L. suspension culture of the family of legume plants (Fabaceae) is low, and therefore there was an attempt to increase it by elicitation. New synthetic substance, 2-(2-fluoro-6-nitrobenzylsulfanyl)pyridine-4-carbothioamide, was tested as elicitor-a substance that showed the best elicitation effect after 48-hour application of 1 mu mol L-1 concentration. Maximum contents of genistin (11.60 mg g(-1) DW), daidzein (8.31 mg g(-1) DW), and genistein (1.50 mg g(-1) DW) were recorded, and the production of these isoflavonoids thus significantly increased, when compared with the control, by 152%, 151%, and 400%. The maximum content of flavonoids (5.78 mg g(-1) DW) and the increase in the productionby 142%, when compared with the control, were induced by 6-hour application of 100 mu mol L-1 concentration. The tested substance showed to be an effective elicitor of phenylpropane metabolism.

Název v anglickém jazyce

New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture

Popis výsledku anglicky

The production of secondary metabolites in Trifolium pratense L. suspension culture of the family of legume plants (Fabaceae) is low, and therefore there was an attempt to increase it by elicitation. New synthetic substance, 2-(2-fluoro-6-nitrobenzylsulfanyl)pyridine-4-carbothioamide, was tested as elicitor-a substance that showed the best elicitation effect after 48-hour application of 1 mu mol L-1 concentration. Maximum contents of genistin (11.60 mg g(-1) DW), daidzein (8.31 mg g(-1) DW), and genistein (1.50 mg g(-1) DW) were recorded, and the production of these isoflavonoids thus significantly increased, when compared with the control, by 152%, 151%, and 400%. The maximum content of flavonoids (5.78 mg g(-1) DW) and the increase in the productionby 142%, when compared with the control, were induced by 6-hour application of 100 mu mol L-1 concentration. The tested substance showed to be an effective elicitor of phenylpropane metabolism.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The Scientific World Journal

ISSN

1537-744X

e-ISSN

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Svazek periodika

2012

Číslo periodika v rámci svazku

2012

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

000303022700001

EID výsledku v databázi Scopus

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