Benzothiazoles - scaffold of interest for CNS targeted drugs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10292871" target="_blank" >RIV/00216208:11160/15:10292871 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60162694:G44__/15:43875336 RIV/62690094:18470/15:50003418 RIV/00179906:_____/15:10292871

Výsledek na webu

<a href="http://benthamscience.com/journals/current-medicinal-chemistry/volume/22/issue/6/page/730/" target="_blank" >http://benthamscience.com/journals/current-medicinal-chemistry/volume/22/issue/6/page/730/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/0929867322666141212120631" target="_blank" >10.2174/0929867322666141212120631</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Benzothiazoles - scaffold of interest for CNS targeted drugs

Popis výsledku v původním jazyce

Benzothiazole compounds represent heterocyclic systems comprising a benzene ring fused with a thiazole ring containing nitrogen and sulphur in its structure. Besides the presence of a benzothiazole core in naturally occurring molecules, synthesized compounds containing a benzothiazole moiety in their structure proved to be a significant class of potential therapeutics, as they exhibit biological effects such as antitumor, antibacterial, antitubercular, antiviral, anthelmintic, antidiabetic and many others. Apart from the aforementioned peripheral or microbial active sites, benzothiazole analogues are also biologically active compounds in the central nervous system, where some approved drugs containing a benzothiazole moiety have already been identifiedand are used in the treatment of various neurological disorders. New benzothiazole molecules are currently under development and are being evaluated for several uses including diagnostics and as therapeutic drug candidates for the treatm

Název v anglickém jazyce

Benzothiazoles - scaffold of interest for CNS targeted drugs

Popis výsledku anglicky

Benzothiazole compounds represent heterocyclic systems comprising a benzene ring fused with a thiazole ring containing nitrogen and sulphur in its structure. Besides the presence of a benzothiazole core in naturally occurring molecules, synthesized compounds containing a benzothiazole moiety in their structure proved to be a significant class of potential therapeutics, as they exhibit biological effects such as antitumor, antibacterial, antitubercular, antiviral, anthelmintic, antidiabetic and many others. Apart from the aforementioned peripheral or microbial active sites, benzothiazole analogues are also biologically active compounds in the central nervous system, where some approved drugs containing a benzothiazole moiety have already been identifiedand are used in the treatment of various neurological disorders. New benzothiazole molecules are currently under development and are being evaluated for several uses including diagnostics and as therapeutic drug candidates for the treatm

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Medicinal Chemistry

ISSN

0929-8673

e-ISSN

—

Svazek periodika

22

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

AE - Spojené arabské emiráty

Počet stran výsledku

18

Strana od-do

730-747

Kód UT WoS článku

000349388600006

EID výsledku v databázi Scopus

2-s2.0-84931265913