Hand grip endurance test relates to clinical state and prognosis in COPD patients better than 6-minute walk test distance

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F17%3A10366562" target="_blank" >RIV/00216208:11160/17:10366562 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/17:10366562

Výsledek na webu

<a href="http://www.dovepress.com/hand-grip-endurance-test-relates-to-clinical-state-and-prognosis-in-co-peer-reviewed-fulltext-article-COPD" target="_blank" >http://www.dovepress.com/hand-grip-endurance-test-relates-to-clinical-state-and-prognosis-in-co-peer-reviewed-fulltext-article-COPD</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/COPD.S144566" target="_blank" >10.2147/COPD.S144566</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hand grip endurance test relates to clinical state and prognosis in COPD patients better than 6-minute walk test distance

Popis výsledku v původním jazyce

Purpose: Patients with COPD present peripheral muscle dysfunction and atrophy, expressed as muscle strength and endurance reduction. The goal of this study was direct dynamometric assessment of hand grip endurance and strength in relation to the stage of disease, multidimensional predictors of mortality, and 6-minute walk test (6MWT). To the best of our knowledge, there has been no previous study determining these parameters. Patients and methods: In this observational study, 58 consecutive outpatients with stable COPD and 25 volunteers without respiratory problems were compared. All COPD subjects underwent a comprehensive examination to determine COPD severity, prognostic scales, and 6MWT. Body composition, basic spirometric parameters, and hand grip strength and endurance were determined in all study participants. Results: Patients in the COPD group had a 15% decrease in maximum strength (P=0.012) and a 28% decrease in area under the force/time curve (AUC) of the endurance test (P&lt;0.001) compared to the control group. Dynamometric parameters were significantly negatively associated with the stage of disease and values of multivariable prediction indexes, and positively associated with the results of 6MWT. In most cases, closer associations were found with AUC than with 6MWT and in the gender-specific groups. Conclusion: Both hand grip strength and endurance are impaired in COPD patients in comparison with the control group. In particular, AUC could be considered as an attractive option not only to assess exercise capacity but also as a predictive marker with a better prognostic value than 6MWT in COPD patients. This is the first study to observe the dependence of hand grip endurance on combined COPD assessment.

Název v anglickém jazyce

Hand grip endurance test relates to clinical state and prognosis in COPD patients better than 6-minute walk test distance

Popis výsledku anglicky

Purpose: Patients with COPD present peripheral muscle dysfunction and atrophy, expressed as muscle strength and endurance reduction. The goal of this study was direct dynamometric assessment of hand grip endurance and strength in relation to the stage of disease, multidimensional predictors of mortality, and 6-minute walk test (6MWT). To the best of our knowledge, there has been no previous study determining these parameters. Patients and methods: In this observational study, 58 consecutive outpatients with stable COPD and 25 volunteers without respiratory problems were compared. All COPD subjects underwent a comprehensive examination to determine COPD severity, prognostic scales, and 6MWT. Body composition, basic spirometric parameters, and hand grip strength and endurance were determined in all study participants. Results: Patients in the COPD group had a 15% decrease in maximum strength (P=0.012) and a 28% decrease in area under the force/time curve (AUC) of the endurance test (P&lt;0.001) compared to the control group. Dynamometric parameters were significantly negatively associated with the stage of disease and values of multivariable prediction indexes, and positively associated with the results of 6MWT. In most cases, closer associations were found with AUC than with 6MWT and in the gender-specific groups. Conclusion: Both hand grip strength and endurance are impaired in COPD patients in comparison with the control group. In particular, AUC could be considered as an attractive option not only to assess exercise capacity but also as a predictive marker with a better prognostic value than 6MWT in COPD patients. This is the first study to observe the dependence of hand grip endurance on combined COPD assessment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30105 - Physiology (including cytology)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Chronic Obstructive Pulmonary Disease

ISSN

1178-2005

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NZ - Nový Zéland

Počet stran výsledku

7

Strana od-do

3429-3435

Kód UT WoS článku

000416966700001

EID výsledku v databázi Scopus

2-s2.0-85037732851