Current state of bioanalytical chromatography in clinical analysis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F18%3A10379469" target="_blank" >RIV/00216208:11160/18:10379469 - isvavai.cz</a>
Výsledek na webu
<a href="http://pubs.rsc.org/en/content/articlehtml/2018/an/c7an01807j" target="_blank" >http://pubs.rsc.org/en/content/articlehtml/2018/an/c7an01807j</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c7an01807j" target="_blank" >10.1039/c7an01807j</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Current state of bioanalytical chromatography in clinical analysis
Popis výsledku v původním jazyce
Chromatographic methods have become popular in clinical analysis in both routine and research laboratories. The purpose of this review article is to provide an overview of the current state of chromatographic methods, i.e., high-performance liquid chromatography (HPLC), gas chromatography (GC), and supercritical fluid chromatography (SFC), in clinical analysis. The aspects related to method sensitivity, selectivity, analysis time, and throughput have been discussed in detail. Adequate solutions to improve these features have also been presented. HPLC is the most widely used method among the chromatographic methods, whereas GC is dedicated to several specific applications, and SFC is used only marginally certainly due to its only recent comeback to the analytical scene. Based on the literature search, the application fields in clinical analysis are divided into the following groups: drugs, hormones, drugs of abuse, metabolomics, lipidomics, volatile organic compounds, biomarkers and endogenous compounds, proteomics, multi-analyte approches, and others. The important features of these applications have been emphasized.
Název v anglickém jazyce
Current state of bioanalytical chromatography in clinical analysis
Popis výsledku anglicky
Chromatographic methods have become popular in clinical analysis in both routine and research laboratories. The purpose of this review article is to provide an overview of the current state of chromatographic methods, i.e., high-performance liquid chromatography (HPLC), gas chromatography (GC), and supercritical fluid chromatography (SFC), in clinical analysis. The aspects related to method sensitivity, selectivity, analysis time, and throughput have been discussed in detail. Adequate solutions to improve these features have also been presented. HPLC is the most widely used method among the chromatographic methods, whereas GC is dedicated to several specific applications, and SFC is used only marginally certainly due to its only recent comeback to the analytical scene. Based on the literature search, the application fields in clinical analysis are divided into the following groups: drugs, hormones, drugs of abuse, metabolomics, lipidomics, volatile organic compounds, biomarkers and endogenous compounds, proteomics, multi-analyte approches, and others. The important features of these applications have been emphasized.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10406 - Analytical chemistry
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
The Analyst
ISSN
0003-2654
e-ISSN
—
Svazek periodika
143
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
21
Strana od-do
1305-1325
Kód UT WoS článku
000428030100002
EID výsledku v databázi Scopus
2-s2.0-85043585778