Mitochondrial replacement therapy in the light of the Convention on Biomedicine: the outline of a dilemma

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11220%2F18%3A10384032" target="_blank" >RIV/00216208:11220/18:10384032 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Mitochondrial replacement therapy in the light of the Convention on Biomedicine: the outline of a dilemma

Popis výsledku v původním jazyce

In recent years, wide media attention has been drawn to the mitochondrial replacement therapy (MRT; or, in journalist jargon, the creation of &quot;the three-parent babies&quot;)- The novel technique enables physicians to treat serious hereditary mitochondrial diseases in embryos by replacing the embryo&apos;s mitochondria carrying the genetic defect with healthy ones. However, the Convention on Human Rights and Biomedicine prohibits any genetic modification that aims at modifying the genome of any descendants. The mitochondrial DNA is inherited in maternal line; therefore, the use of MRT in embryos of female sex could be inadmissible, while in embryos of male sex it could be permissible. This approach, however, might be considered discriminatory. The article analyses basic legal, biological, and ethical questions that require answers in order to solve the said dilemma.

Název v anglickém jazyce

Mitochondrial replacement therapy in the light of the Convention on Biomedicine: the outline of a dilemma

Popis výsledku anglicky

In recent years, wide media attention has been drawn to the mitochondrial replacement therapy (MRT; or, in journalist jargon, the creation of &quot;the three-parent babies&quot;)- The novel technique enables physicians to treat serious hereditary mitochondrial diseases in embryos by replacing the embryo&apos;s mitochondria carrying the genetic defect with healthy ones. However, the Convention on Human Rights and Biomedicine prohibits any genetic modification that aims at modifying the genome of any descendants. The mitochondrial DNA is inherited in maternal line; therefore, the use of MRT in embryos of female sex could be inadmissible, while in embryos of male sex it could be permissible. This approach, however, might be considered discriminatory. The article analyses basic legal, biological, and ethical questions that require answers in order to solve the said dilemma.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

50501 - Law

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Czech Yearbook of Public and Private International Law, česká ročenka mezinárodního práva veřejného a soukromého

ISSN

1805-0565

e-ISSN

—

Svazek periodika

2018

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

16

Strana od-do

280-295

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85060819960