Chiral Separation of Binaphthyl Catalysts Using New Chiral Stationary Phases Based on Derivatized Cyclofructans

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Chiral Separation of Binaphthyl Catalysts Using New Chiral Stationary Phases Based on Derivatized Cyclofructans

Popis výsledku v původním jazyce

Cyclofructans as a completely new and promising class of chiral selectors have been introduced last year for application in separation techniques such as liquid chromatography and capillary electrophoresis. Mainly derivatives of cyclofructans perform interesting separation possibilities for a variety of compounds. The aromatic derivatized cyclofructans composed of six D-fructofuranose units (CF6) have exhibited the most interesting properties and unique enantioselectivity. In this work, two derivatizedcyclofructan-based chiral stationary phases, RN-CF6 ( -naphthylethyl carbamate CF6) and DMP-CF7 (dimethylphenyl carbamate CF7) were used for enantioseparation of substituted binaphtyl catalysts, widely used to control asymmetric processes. Normal separation mode, i.e. mobile phase composed of hexane and propane-2-ol in different ratios was applied and the enantioselectivity of the employed stationary phases was compared.

Název v anglickém jazyce

Chiral Separation of Binaphthyl Catalysts Using New Chiral Stationary Phases Based on Derivatized Cyclofructans

Popis výsledku anglicky

Cyclofructans as a completely new and promising class of chiral selectors have been introduced last year for application in separation techniques such as liquid chromatography and capillary electrophoresis. Mainly derivatives of cyclofructans perform interesting separation possibilities for a variety of compounds. The aromatic derivatized cyclofructans composed of six D-fructofuranose units (CF6) have exhibited the most interesting properties and unique enantioselectivity. In this work, two derivatizedcyclofructan-based chiral stationary phases, RN-CF6 ( -naphthylethyl carbamate CF6) and DMP-CF7 (dimethylphenyl carbamate CF7) were used for enantioseparation of substituted binaphtyl catalysts, widely used to control asymmetric processes. Normal separation mode, i.e. mobile phase composed of hexane and propane-2-ol in different ratios was applied and the enantioselectivity of the employed stationary phases was compared.

Druh

D - Stať ve sborníku

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 6th International Students Conference"Modern Analytical Chemistry"

ISBN

978-80-7444-005-2

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

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Název nakladatele

Univerzita Karlova v Praze, Přírodovědecká fakulta

Místo vydání

Praha

Místo konání akce

Praha, Česká republika

Datum konání akce

23. 9. 2010

Typ akce podle státní příslušnosti

CST - Celostátní akce

Kód UT WoS článku

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