Methods for determination of all binding parameters in systems with simultaneous borate and cyclodextrin complexation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10099392" target="_blank" >RIV/00216208:11310/11:10099392 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.chroma.2011.07.088" target="_blank" >http://dx.doi.org/10.1016/j.chroma.2011.07.088</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2011.07.088" target="_blank" >10.1016/j.chroma.2011.07.088</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Methods for determination of all binding parameters in systems with simultaneous borate and cyclodextrin complexation

Popis výsledku v původním jazyce

Two novel methods for determination of binding constants in the systems with borate and cyclodextrin complexation were developed. The methods enable to determine all binding parameters in these systems and even the binding constants of interaction of a neutral analyte with a neutral cyclodextrin. The first method is based on nonlinear fitting of experimental data and further evaluation of fitting parameters. The second method requires a multiple regression. The methods provide identical results with lowexperimental error. Only one set of measurements is required for both methods. Thus the binding parameters can be mutually compared. The binding parameters for neutral analytes ((R,R)-(+)-hydrobenzoin and (S,S)-(-)-hydrobenzoin) and neutral cyclodextrin(heptakis(2,6-di-O-methyl)-beta-cyclodextrin) were evaluated and the effect of individual types of interaction was revealed.

Název v anglickém jazyce

Methods for determination of all binding parameters in systems with simultaneous borate and cyclodextrin complexation

Popis výsledku anglicky

Two novel methods for determination of binding constants in the systems with borate and cyclodextrin complexation were developed. The methods enable to determine all binding parameters in these systems and even the binding constants of interaction of a neutral analyte with a neutral cyclodextrin. The first method is based on nonlinear fitting of experimental data and further evaluation of fitting parameters. The second method requires a multiple regression. The methods provide identical results with lowexperimental error. Only one set of measurements is required for both methods. Thus the binding parameters can be mutually compared. The binding parameters for neutral analytes ((R,R)-(+)-hydrobenzoin and (S,S)-(-)-hydrobenzoin) and neutral cyclodextrin(heptakis(2,6-di-O-methyl)-beta-cyclodextrin) were evaluated and the effect of individual types of interaction was revealed.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F08%2F1428" target="_blank" >GA203/08/1428: Kapilární elektroforéza s multidimenzionální detekcí a její užití pro separaci a charakterizaci biopolymerů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

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Svazek periodika

1218

Číslo periodika v rámci svazku

40

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

7211-7218

Kód UT WoS článku

000295300600017

EID výsledku v databázi Scopus

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