Ultrafine particles are not major carriers of carcinogenic PAHs and their genotoxicity in size-segregated aerosols

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10140202" target="_blank" >RIV/00216208:11310/13:10140202 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/13:00395359

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.mrgentox.2012.12.016" target="_blank" >http://dx.doi.org/10.1016/j.mrgentox.2012.12.016</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mrgentox.2012.12.016" target="_blank" >10.1016/j.mrgentox.2012.12.016</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ultrafine particles are not major carriers of carcinogenic PAHs and their genotoxicity in size-segregated aerosols

Popis výsledku v původním jazyce

Some studies suggest that genotoxic effects of combustion-related aerosols are induced by carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) and their derivatives, which are part of the organic fraction of the particulate matter (PM) in ambient air.The proportion of the organic fraction in PM is known to vary with particle size. The ultrafine fraction is hypothesized to be the most important carrier of c-PAHs, since it possesses the highest specific surface area of PM. To test this hypothesis, thedistribution of c-PAHs in organic extracts (EOMs) was compared for four size fractions of ambient-air aerosols: coarse (1< d(ae)< 10 mu m), upper (0.5 <d(ae)< 1 mu m), and lower (0.17<d(ae)<0.5 mu m) accumulation aerosol particles and ultrafine particles(d(ae)<0.17). High-volume aerosol samples were collected consecutively in four localities that differed in the level of environmental pollution. The genotoxicity of EOMs was measured by analysis of DNA adducts induced in an a cellular as

Název v anglickém jazyce

Ultrafine particles are not major carriers of carcinogenic PAHs and their genotoxicity in size-segregated aerosols

Popis výsledku anglicky

Some studies suggest that genotoxic effects of combustion-related aerosols are induced by carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) and their derivatives, which are part of the organic fraction of the particulate matter (PM) in ambient air.The proportion of the organic fraction in PM is known to vary with particle size. The ultrafine fraction is hypothesized to be the most important carrier of c-PAHs, since it possesses the highest specific surface area of PM. To test this hypothesis, thedistribution of c-PAHs in organic extracts (EOMs) was compared for four size fractions of ambient-air aerosols: coarse (1< d(ae)< 10 mu m), upper (0.5 <d(ae)< 1 mu m), and lower (0.17<d(ae)<0.5 mu m) accumulation aerosol particles and ultrafine particles(d(ae)<0.17). High-volume aerosol samples were collected consecutively in four localities that differed in the level of environmental pollution. The genotoxicity of EOMs was measured by analysis of DNA adducts induced in an a cellular as

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DI - Znečištění a kontrola vzduchu

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

ISSN

1383-5718

e-ISSN

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Svazek periodika

754

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

1-6

Kód UT WoS článku

000320495200001

EID výsledku v databázi Scopus

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