Formation and stability of calcium complexes of dimethyl sulfoxide in water

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10271747" target="_blank" >RIV/00216208:11310/14:10271747 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388963:_____/14:00427705 RIV/60460709:41210/14:63674

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ijms.2014.01.001" target="_blank" >http://dx.doi.org/10.1016/j.ijms.2014.01.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijms.2014.01.001" target="_blank" >10.1016/j.ijms.2014.01.001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Formation and stability of calcium complexes of dimethyl sulfoxide in water

Popis výsledku v původním jazyce

Dimethyl sulfoxide (DMSO) is widely utilized compound in biomedical and technological applications. Predominantly, it is used for biomembranes opening during a drug delivery procedure. The mechanism of DMSO membrane treatment is influenced by DMSO interactions with Ca2+ as well as with water presence. In this study we investigate Ca2+ interactions with DMSO in an aqueous environment using electrospray ionization mass spectrometry supported by density functional calculations. The number of DMSO ligands in [Ca(DMSO)(x)](2+) depends on the conditions during the electrospray and ion-transfer process. At capillary temperatures lower than 120 degrees C the complexes with a high number of DMSO are preferentially transferred to the gas phase (e.g. [Ca(DMSO)(6)](2+)). With increasing temperature the number of DMSO ligands decreases while they are replaced with water molecules. Both the experiment and the calculations show that the bonding energy of DMSO to Ca2+ is strongly influenced by the pre

Název v anglickém jazyce

Formation and stability of calcium complexes of dimethyl sulfoxide in water

Popis výsledku anglicky

Dimethyl sulfoxide (DMSO) is widely utilized compound in biomedical and technological applications. Predominantly, it is used for biomembranes opening during a drug delivery procedure. The mechanism of DMSO membrane treatment is influenced by DMSO interactions with Ca2+ as well as with water presence. In this study we investigate Ca2+ interactions with DMSO in an aqueous environment using electrospray ionization mass spectrometry supported by density functional calculations. The number of DMSO ligands in [Ca(DMSO)(x)](2+) depends on the conditions during the electrospray and ion-transfer process. At capillary temperatures lower than 120 degrees C the complexes with a high number of DMSO are preferentially transferred to the gas phase (e.g. [Ca(DMSO)(6)](2+)). With increasing temperature the number of DMSO ligands decreases while they are replaced with water molecules. Both the experiment and the calculations show that the bonding energy of DMSO to Ca2+ is strongly influenced by the pre

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GP13-21409P" target="_blank" >GP13-21409P: Interakce kovů a živin s významnými pesticidy v půdě a na biomembránách</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Mass Spectrometry

ISSN

1387-3806

e-ISSN

—

Svazek periodika

360

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

8-14

Kód UT WoS článku

000332440800002

EID výsledku v databázi Scopus

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