Laparoscopic Greater Curvature Plication in Morbidly Obese Women with Type 2 Diabetes: Effects on Glucose Homeostasis, Postprandial Triglyceridemia and Selected Gut Hormones

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10283818" target="_blank" >RIV/00216208:11310/14:10283818 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023761:_____/14:#0000448

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11695-013-1143-4" target="_blank" >http://dx.doi.org/10.1007/s11695-013-1143-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11695-013-1143-4" target="_blank" >10.1007/s11695-013-1143-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Laparoscopic Greater Curvature Plication in Morbidly Obese Women with Type 2 Diabetes: Effects on Glucose Homeostasis, Postprandial Triglyceridemia and Selected Gut Hormones

Popis výsledku v původním jazyce

Background Laparoscopic greater curvature plication (LGCP) is an emerging bariatric procedure that reduces the gastric volume without implantable devices or gastrectomy. The aim of this study was to explore changes in glucose homeostasis, postprandial triglyceridemia, and meal-stimulated secretion of selected gut hormones [glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), ghrelin, and obestatin] in patients with type 2 diabetes mellitus (T2DM) at 1 and 6 months after the procedure. Methods Thirteen morbidly obese T2DM women (mean age, 53.2 +/- 8.76 years; body mass index, 40.1 +/- 4.59 kg/m(2)) were prospectively investigated before the LGCP and at 1- and 6-month follow-up. At these time points, all study patients underwent a standardized liquid mixed-meal test, and blood was sampled for assessment of plasma levels of glucose, insulin, C-peptide, triglycerides, GIP, GLP-1, ghrelin, and obestatin. Results All patients had significant weight loss both a

Název v anglickém jazyce

Laparoscopic Greater Curvature Plication in Morbidly Obese Women with Type 2 Diabetes: Effects on Glucose Homeostasis, Postprandial Triglyceridemia and Selected Gut Hormones

Popis výsledku anglicky

Background Laparoscopic greater curvature plication (LGCP) is an emerging bariatric procedure that reduces the gastric volume without implantable devices or gastrectomy. The aim of this study was to explore changes in glucose homeostasis, postprandial triglyceridemia, and meal-stimulated secretion of selected gut hormones [glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), ghrelin, and obestatin] in patients with type 2 diabetes mellitus (T2DM) at 1 and 6 months after the procedure. Methods Thirteen morbidly obese T2DM women (mean age, 53.2 +/- 8.76 years; body mass index, 40.1 +/- 4.59 kg/m(2)) were prospectively investigated before the LGCP and at 1- and 6-month follow-up. At these time points, all study patients underwent a standardized liquid mixed-meal test, and blood was sampled for assessment of plasma levels of glucose, insulin, C-peptide, triglycerides, GIP, GLP-1, ghrelin, and obestatin. Results All patients had significant weight loss both a

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Obesity Surgery

ISSN

0960-8923

e-ISSN

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Svazek periodika

24

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CA - Kanada

Počet stran výsledku

9

Strana od-do

718-726

Kód UT WoS článku

000334268000008

EID výsledku v databázi Scopus

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