Glucose homeostasis and insulin resistance: prevalence, gender differences and predictors in adolescents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10289031" target="_blank" >RIV/00216208:11310/14:10289031 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/14:43909080 RIV/00023761:_____/14:#0000442

Výsledek na webu

<a href="http://dx.doi.org/10.1186/1758-5996-6-100" target="_blank" >http://dx.doi.org/10.1186/1758-5996-6-100</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1758-5996-6-100" target="_blank" >10.1186/1758-5996-6-100</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Glucose homeostasis and insulin resistance: prevalence, gender differences and predictors in adolescents

Popis výsledku v původním jazyce

Background: Adolescence, due to transient pubertal insulin resistance (IR), is associated with a higher risk for disturbances of glucose metabolism. The aim of our study was 1) to investigate the prevalence of disturbances of glucose metabolism, 2) to define gender specific homeostasis model assessment of insulin resistance (HOMA-IR) thresholds associated with increased cardiometabolic risks and 3) to provide predictors of HOMA-IR. Methods: The studied cohort consisted of Czech adolescents aged 13.0-17.9 years: 1,518 individuals of general population and three studied groups according weight category (615 normal weight, 230 overweight and 683 obese). The prevalence of IR, impaired fasting glucose (IFG) and type 2 diabetes was assessed. Risky HOMA-IR thresholds based on components of metabolic syndrome were investigated. HOMA-IR prediction was calculated taking into account age, blood pressure, multiple anthropometric, biochemical and hormonal parameters. Results: In general population

Název v anglickém jazyce

Glucose homeostasis and insulin resistance: prevalence, gender differences and predictors in adolescents

Popis výsledku anglicky

Background: Adolescence, due to transient pubertal insulin resistance (IR), is associated with a higher risk for disturbances of glucose metabolism. The aim of our study was 1) to investigate the prevalence of disturbances of glucose metabolism, 2) to define gender specific homeostasis model assessment of insulin resistance (HOMA-IR) thresholds associated with increased cardiometabolic risks and 3) to provide predictors of HOMA-IR. Methods: The studied cohort consisted of Czech adolescents aged 13.0-17.9 years: 1,518 individuals of general population and three studied groups according weight category (615 normal weight, 230 overweight and 683 obese). The prevalence of IR, impaired fasting glucose (IFG) and type 2 diabetes was assessed. Risky HOMA-IR thresholds based on components of metabolic syndrome were investigated. HOMA-IR prediction was calculated taking into account age, blood pressure, multiple anthropometric, biochemical and hormonal parameters. Results: In general population

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Diabetology and Metabolic Syndrome

ISSN

1758-5996

e-ISSN

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Svazek periodika

6

Číslo periodika v rámci svazku

September 2014

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

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Kód UT WoS článku

000343774500001

EID výsledku v databázi Scopus

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