Voltammetric Determination of 2-Aminofluoren-9-one and Investigation of Its Interaction with DNA on a Glassy Carbon Electrode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10291008" target="_blank" >RIV/00216208:11310/15:10291008 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/elan.201400427" target="_blank" >http://dx.doi.org/10.1002/elan.201400427</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elan.201400427" target="_blank" >10.1002/elan.201400427</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Voltammetric Determination of 2-Aminofluoren-9-one and Investigation of Its Interaction with DNA on a Glassy Carbon Electrode

Popis výsledku v původním jazyce

Voltammetric behavior of the genotoxic environmental pollutant 2-aminofluoren-9-one (2-AFN) was investigated using direct current voltammetry (DCV) and differential pulse voltammetry (DPV) at a glassy carbon electrode (GCE) in both negative and positivepotential regions. For the determination of 2-AFN based on the cathodic reduction of the carbonyl group, optimum conditions were found in a methanol-Britton-Robinson (BR) buffer pH 4.0 (1 : 9, v/v) medium, with the limits of quantification (L(Q)s) of 0.4and 0.2 mu mol L-1 for DCV and DPV, respectively. For the determination of 2-AFN based on the anodic oxidation of the amino group, optimum conditions were found in a mixture of methanol-BR buffer pH 8.0 (1 : 9, v/v), with the L(Q)s of 0.8 and 0.6 mu molL-1 for DCV and DPV, respectively. The practical applicability of the newly developed voltammetric methods was verified on the direct determination of 2-AFN in model samples of drinking and river water. Moreover, the interaction between

Název v anglickém jazyce

Voltammetric Determination of 2-Aminofluoren-9-one and Investigation of Its Interaction with DNA on a Glassy Carbon Electrode

Popis výsledku anglicky

Voltammetric behavior of the genotoxic environmental pollutant 2-aminofluoren-9-one (2-AFN) was investigated using direct current voltammetry (DCV) and differential pulse voltammetry (DPV) at a glassy carbon electrode (GCE) in both negative and positivepotential regions. For the determination of 2-AFN based on the cathodic reduction of the carbonyl group, optimum conditions were found in a methanol-Britton-Robinson (BR) buffer pH 4.0 (1 : 9, v/v) medium, with the limits of quantification (L(Q)s) of 0.4and 0.2 mu mol L-1 for DCV and DPV, respectively. For the determination of 2-AFN based on the anodic oxidation of the amino group, optimum conditions were found in a mixture of methanol-BR buffer pH 8.0 (1 : 9, v/v), with the L(Q)s of 0.8 and 0.6 mu molL-1 for DCV and DPV, respectively. The practical applicability of the newly developed voltammetric methods was verified on the direct determination of 2-AFN in model samples of drinking and river water. Moreover, the interaction between

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

—

Projekt

<a href="/cs/project/GP13-23337P" target="_blank" >GP13-23337P: Komplexní diagnostický přístup při hodnocení interakce DNA s organickými xenobiotiky pomocí elektrochemických nanostrukturovaných DNA biosenzorů</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electroanalysis

ISSN

1040-0397

e-ISSN

—

Svazek periodika

27

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

10

Strana od-do

101-110

Kód UT WoS článku

000347838300013

EID výsledku v databázi Scopus

2-s2.0-84920939795