New flow-through coulometric detector with renewable working electrode material for flow injection analysis and HPLC

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10293509" target="_blank" >RIV/00216208:11310/15:10293509 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.electacta.2014.12.091" target="_blank" >http://dx.doi.org/10.1016/j.electacta.2014.12.091</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.electacta.2014.12.091" target="_blank" >10.1016/j.electacta.2014.12.091</a>

Jazyk výsledku

angličtina

Název v původním jazyce

New flow-through coulometric detector with renewable working electrode material for flow injection analysis and HPLC

Popis výsledku v původním jazyce

Newly developed flow-through coulometric detector with renewable working material of glassy carbon microbeads was fabricated and its basic electrochemical parameters were studied by flow injection analysis using potassium ferrocyanide and hydroquinone asprobes. Main advantage of the detector is its simple construction while maintaining good electrochemical parameters and high conversion degree. Practical application of the detector was proved by the development of new HPLC and FIA method of thymol andsulfamethizole determination in pharmaceutical preparations. Optimal determination conditions were found and calibration dependences were measured. A value of quantification limit 0.97 mu mol L (1) for thymol and 0.040 mu mol L (1) for sulfamethizole were obtained. Newly developed methods were used for determination of the studied compounds in pharmaceutical preparations. HPLC with spectrophotometric detection was used as a comparative method; results from both methods were in good agree

Název v anglickém jazyce

New flow-through coulometric detector with renewable working electrode material for flow injection analysis and HPLC

Popis výsledku anglicky

Newly developed flow-through coulometric detector with renewable working material of glassy carbon microbeads was fabricated and its basic electrochemical parameters were studied by flow injection analysis using potassium ferrocyanide and hydroquinone asprobes. Main advantage of the detector is its simple construction while maintaining good electrochemical parameters and high conversion degree. Practical application of the detector was proved by the development of new HPLC and FIA method of thymol andsulfamethizole determination in pharmaceutical preparations. Optimal determination conditions were found and calibration dependences were measured. A value of quantification limit 0.97 mu mol L (1) for thymol and 0.040 mu mol L (1) for sulfamethizole were obtained. Newly developed methods were used for determination of the studied compounds in pharmaceutical preparations. HPLC with spectrophotometric detection was used as a comparative method; results from both methods were in good agree

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

—

Projekt

<a href="/cs/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Centrum nových přístupů k bioanalýze a molekulární diagnostice</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electrochimica Acta

ISSN

0013-4686

e-ISSN

—

Svazek periodika

154

Číslo periodika v rámci svazku

February

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

397

Strana od-do

397-403

Kód UT WoS článku

000349546500052

EID výsledku v databázi Scopus

2-s2.0-84919807907