Nafion membranes modified by cationic cyclodextrin derivatives for enantioselective separation
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F21%3A10428480" target="_blank" >RIV/00216208:11310/21:10428480 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/67985858:_____/21:00540919
Výsledek na webu
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=kcSJEiuD9J" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=kcSJEiuD9J</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.seppur.2021.118538" target="_blank" >10.1016/j.seppur.2021.118538</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Nafion membranes modified by cationic cyclodextrin derivatives for enantioselective separation
Popis výsledku v původním jazyce
Nafion117 (R) membranes modified by three cationic cyclodextrin (CD) derivatives have been prepared by strong ionic bonding. All CD derivatives contained bis(methylimidazolium) (MIM2) cationic anchor covalently bound to the CD unit, either using no spacer or using diethylene glycol (DEG) or tetraethylene glycol (TEEG) spacers. The modified membranes were tested in chiral separation of a model racemic mixture (D/L-tryptophan) from water. Different experimental set-ups for characterising membranes in enantioselective separation - pertraction, two kinds of sorption, and pressure-driven membrane separation - have been described and rigorously compared. The membranes CD-MIM2, CD-DEG-MIM2 have reached the highest enantiomeric excess, 14 and 44% respectively, in 280 days. The lowest performance of the CD-TEEG-MIM2 membrane, with the long spacer, has been visibly ameliorated by applying pertraction; enantiomeric excess rose from 2 to 27% in 80 days. Even though sorption played the main role in pertraction, this process substantially enhanced the separation of racemic mixtures. The pressure-driven approach has allowed the operation to be continuous and faster, which has the potential for continuous large-scale production of enantiopure compounds and could pave the way for many more commercial applications, satisfying the considerable demand for large-scale chiral separation techniques.
Název v anglickém jazyce
Nafion membranes modified by cationic cyclodextrin derivatives for enantioselective separation
Popis výsledku anglicky
Nafion117 (R) membranes modified by three cationic cyclodextrin (CD) derivatives have been prepared by strong ionic bonding. All CD derivatives contained bis(methylimidazolium) (MIM2) cationic anchor covalently bound to the CD unit, either using no spacer or using diethylene glycol (DEG) or tetraethylene glycol (TEEG) spacers. The modified membranes were tested in chiral separation of a model racemic mixture (D/L-tryptophan) from water. Different experimental set-ups for characterising membranes in enantioselective separation - pertraction, two kinds of sorption, and pressure-driven membrane separation - have been described and rigorously compared. The membranes CD-MIM2, CD-DEG-MIM2 have reached the highest enantiomeric excess, 14 and 44% respectively, in 280 days. The lowest performance of the CD-TEEG-MIM2 membrane, with the long spacer, has been visibly ameliorated by applying pertraction; enantiomeric excess rose from 2 to 27% in 80 days. Even though sorption played the main role in pertraction, this process substantially enhanced the separation of racemic mixtures. The pressure-driven approach has allowed the operation to be continuous and faster, which has the potential for continuous large-scale production of enantiopure compounds and could pave the way for many more commercial applications, satisfying the considerable demand for large-scale chiral separation techniques.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10401 - Organic chemistry
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Separation and Purification Technology
ISSN
1383-5866
e-ISSN
—
Svazek periodika
266
Číslo periodika v rámci svazku
July
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
10
Strana od-do
118538
Kód UT WoS článku
000647567000006
EID výsledku v databázi Scopus
2-s2.0-85102647289