Phenotype and function of macrophages is regulated by chemokines

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F24%3A10487934" target="_blank" >RIV/00216208:11310/24:10487934 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/B978-0-12-821754-2.00003-5" target="_blank" >https://doi.org/10.1016/B978-0-12-821754-2.00003-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/B978-0-12-821754-2.00003-5" target="_blank" >10.1016/B978-0-12-821754-2.00003-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Phenotype and function of macrophages is regulated by chemokines

Popis výsledku v původním jazyce

Chemokines play a pivotal role in regulating immune processes, orchestrating the recruitment and activation of immune cells, including macrophages. This dynamic interplay between chemokines and macrophages influences macrophage migration, activation, and polarization in both physiological and pathological contexts. This chapter describes specific examples of chemokine-mediated effects on macrophages in musculoskeletal diseases, including bone remodeling, osteoarthritis, osteoporosis, and rheumatoid arthritis. Understanding of interplay between chemokines and macrophages holds promise for the development of targeted therapeutic strategies, and furthermore, serum chemokine levels can serve as promising predictive markers of disease severity.

Název v anglickém jazyce

Phenotype and function of macrophages is regulated by chemokines

Popis výsledku anglicky

Chemokines play a pivotal role in regulating immune processes, orchestrating the recruitment and activation of immune cells, including macrophages. This dynamic interplay between chemokines and macrophages influences macrophage migration, activation, and polarization in both physiological and pathological contexts. This chapter describes specific examples of chemokine-mediated effects on macrophages in musculoskeletal diseases, including bone remodeling, osteoarthritis, osteoporosis, and rheumatoid arthritis. Understanding of interplay between chemokines and macrophages holds promise for the development of targeted therapeutic strategies, and furthermore, serum chemokine levels can serve as promising predictive markers of disease severity.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

30102 - Immunology

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Macrophages Biology and Tissue Inflammation in Health and Disease

ISBN

978-0-12-821754-2

Počet stran výsledku

12

Strana od-do

37-48

Počet stran knihy

366

Název nakladatele

Academic Press, Elsevier

Místo vydání

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Kód UT WoS kapitoly

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