Sensitive Raman spectroscopy of lipids based on drop deposition using DCDR and SERS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F13%3A10192716" target="_blank" >RIV/00216208:11320/13:10192716 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/jrs.4364" target="_blank" >http://dx.doi.org/10.1002/jrs.4364</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jrs.4364" target="_blank" >10.1002/jrs.4364</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Sensitive Raman spectroscopy of lipids based on drop deposition using DCDR and SERS

Popis výsledku v původním jazyce

Raman spectroscopy is widely used for study of lipids and membrane models. A severe limitation of this technique lies in the low Raman cross section requiring high sample concentrations. We report sensitive detection of synthetic 1,2-dimyristoyl-3-trimethylammonium-propane (DMTAP) lipid employing two Raman techniques with improved sensitivity: drop coating deposition Raman (DCDR) and surface-enhanced Raman scattering (SERS) spectroscopies. DCDR provided well-reproducible DMTAP spectra without considerable loss of its solution properties if measured from the coffee ring' pattern of a drop dried on a SpectRIM(TM) plate. DMTAP was detected at similar to 10 M initial solution concentration, which is about three orders of magnitude lower than that for conventional Raman spectroscopy. Moreover, SERS spectra from dried ring of Ag hydrosol/DMTAP system were obtained down to similar to 0.3 M DMTAP concentration, which means that sensitivity of SERS is about five orders of magnitude higher than

Název v anglickém jazyce

Sensitive Raman spectroscopy of lipids based on drop deposition using DCDR and SERS

Popis výsledku anglicky

Raman spectroscopy is widely used for study of lipids and membrane models. A severe limitation of this technique lies in the low Raman cross section requiring high sample concentrations. We report sensitive detection of synthetic 1,2-dimyristoyl-3-trimethylammonium-propane (DMTAP) lipid employing two Raman techniques with improved sensitivity: drop coating deposition Raman (DCDR) and surface-enhanced Raman scattering (SERS) spectroscopies. DCDR provided well-reproducible DMTAP spectra without considerable loss of its solution properties if measured from the coffee ring' pattern of a drop dried on a SpectRIM(TM) plate. DMTAP was detected at similar to 10 M initial solution concentration, which is about three orders of magnitude lower than that for conventional Raman spectroscopy. Moreover, SERS spectra from dried ring of Ag hydrosol/DMTAP system were obtained down to similar to 0.3 M DMTAP concentration, which means that sensitivity of SERS is about five orders of magnitude higher than

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

<a href="/cs/project/GBP205%2F12%2FG118" target="_blank" >GBP205/12/G118: Nanobiofotonika pro medicínu budoucnosti</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Raman Spectroscopy

ISSN

0377-0486

e-ISSN

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Svazek periodika

44

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

1479-1482

Kód UT WoS článku

000330107900001

EID výsledku v databázi Scopus

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