Mechanisms of Aggregation of Cysteine Functionalized Gold Nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F14%3A10288976" target="_blank" >RIV/00216208:11320/14:10288976 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1021/jp502401w" target="_blank" >http://dx.doi.org/10.1021/jp502401w</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/jp502401w" target="_blank" >10.1021/jp502401w</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mechanisms of Aggregation of Cysteine Functionalized Gold Nanoparticles

Popis výsledku v původním jazyce

The interaction of gold nanoparticles (AuNPs) with cysteine and its derivatives is the basis of a number of bionanotechnologies, and for these, the most important process is aggregation (or antiaggregation), which enables an array of colorimetric detection methods. When AuNPs were functionalized with cysteine, its dimer cystine, or the cysteine-derived tripeptide, glutathione, three different mechanisms of aggregation were observed. Both cysteine and glutathione induced aggregation of AuNPs without further pH modification: the first by interparticle zwitterionic interaction and the second by interparticle hydrogen bonding. Cystine, however, did not induce aggregation, although it dissociated into two cysteinate moieties upon adsorption on the AuNPs, which appear to be chemically identical to cysteinate produced from cysteine adsorption. We show that the difference is due to the lower coverage of cysteinate from cystine and differences in charge states of the adsorbates. On modifying th

Název v anglickém jazyce

Mechanisms of Aggregation of Cysteine Functionalized Gold Nanoparticles

Popis výsledku anglicky

The interaction of gold nanoparticles (AuNPs) with cysteine and its derivatives is the basis of a number of bionanotechnologies, and for these, the most important process is aggregation (or antiaggregation), which enables an array of colorimetric detection methods. When AuNPs were functionalized with cysteine, its dimer cystine, or the cysteine-derived tripeptide, glutathione, three different mechanisms of aggregation were observed. Both cysteine and glutathione induced aggregation of AuNPs without further pH modification: the first by interparticle zwitterionic interaction and the second by interparticle hydrogen bonding. Cystine, however, did not induce aggregation, although it dissociated into two cysteinate moieties upon adsorption on the AuNPs, which appear to be chemically identical to cysteinate produced from cysteine adsorption. We show that the difference is due to the lower coverage of cysteinate from cystine and differences in charge states of the adsorbates. On modifying th

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BM - Fyzika pevných látek a magnetismus

OECD FORD obor

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Projekt

<a href="/cs/project/LG12003" target="_blank" >LG12003: Optická dráha materiálového výzkumu na synchrotronu Elettra v Terstu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Physical Chemistry C

ISSN

1932-7447

e-ISSN

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Svazek periodika

118

Číslo periodika v rámci svazku

19

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

10481-10487

Kód UT WoS článku

000336198900073

EID výsledku v databázi Scopus

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