Photodiagnostics and Luminescence Diagnostics of Cancer

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Photodiagnostics and Luminescence Diagnostics of Cancer

Popis výsledku v původním jazyce

Luminescence spectroscopy gains attention as a tool for medical diagnosis, since it can provide prompt diagnostic results at low cost with minimal or none at all invasiveness. Photosensitizers, fluorescent drugs for photodynamic therapy selectively uptaken in diseased tissues, enable identification and demarcation of lesions thanks to its intense emission, which is easy to detect. However, the attention turns towards employment of tissue autofluorescence to distinguish between healthy and diseased tissues. Autofluorescence requires no extrinsic drugs as it utilizes emission of naturally occurring cofactors. This offers another advantage, as the emission of cofactors reveals information about metabolic state of the cells. However, the autofluorescence of tissues is rather weak and emission of particular cofactors often overlaps. This requires employment of time-resolved detection, which offers excellent sensitivity and ability to distinguish emission from individual fluorophores based o

Název v anglickém jazyce

Photodiagnostics and Luminescence Diagnostics of Cancer

Popis výsledku anglicky

Luminescence spectroscopy gains attention as a tool for medical diagnosis, since it can provide prompt diagnostic results at low cost with minimal or none at all invasiveness. Photosensitizers, fluorescent drugs for photodynamic therapy selectively uptaken in diseased tissues, enable identification and demarcation of lesions thanks to its intense emission, which is easy to detect. However, the attention turns towards employment of tissue autofluorescence to distinguish between healthy and diseased tissues. Autofluorescence requires no extrinsic drugs as it utilizes emission of naturally occurring cofactors. This offers another advantage, as the emission of cofactors reveals information about metabolic state of the cells. However, the autofluorescence of tissues is rather weak and emission of particular cofactors often overlaps. This requires employment of time-resolved detection, which offers excellent sensitivity and ability to distinguish emission from individual fluorophores based o

Druh

D - Stať ve sborníku

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

WDS 2014 - Proceedings of Contributed Papers - - Physics

ISBN

978-80-7378-276-4

ISSN

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e-ISSN

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Počet stran výsledku

8

Strana od-do

113-120

Název nakladatele

Matfyzpress

Místo vydání

Prague

Místo konání akce

Prague

Datum konání akce

3. 6. 2014

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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