The muscle-bone interaction in Turner syndrome
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F15%3A10294458" target="_blank" >RIV/00216208:11320/15:10294458 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11130/15:10294458 RIV/00064203:_____/15:10294458
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.bone.2015.01.017" target="_blank" >http://dx.doi.org/10.1016/j.bone.2015.01.017</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bone.2015.01.017" target="_blank" >10.1016/j.bone.2015.01.017</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The muscle-bone interaction in Turner syndrome
Popis výsledku v původním jazyce
Objectives: Turner syndrome (TS) is associated with an increased fracture rate due to reduced bone strength, which is mainly determined by skeletal muscle force. This study aimed to assess the muscle force-bone strength relationship in TS and to compareit with that of healthy controls. Methods: This study included 39 girls with TS and 67 healthy control girls. Maximum muscle force (F-max) was assessed through multiple one-legged hopping with jumping mechanography. Peripheral quantitative computerized tomography assessed the bone strength index at the tibial metaphysis (BSI 4) and the polar strength-strain index at the diaphysis (SSI polar 66). The effect of TS on the muscle-bone unit was tested using multiple linear regression. Results: TS had no impact on F-max (p = 0.14); however, a negative effect on bone strength (p <0.001 for BSI 4 and p <0.01 for SSI polar 66) was observed compared with healthy controls. Bone strength was lower in the TS group (by 18%, p <0.01, for BSI 4 and by
Název v anglickém jazyce
The muscle-bone interaction in Turner syndrome
Popis výsledku anglicky
Objectives: Turner syndrome (TS) is associated with an increased fracture rate due to reduced bone strength, which is mainly determined by skeletal muscle force. This study aimed to assess the muscle force-bone strength relationship in TS and to compareit with that of healthy controls. Methods: This study included 39 girls with TS and 67 healthy control girls. Maximum muscle force (F-max) was assessed through multiple one-legged hopping with jumping mechanography. Peripheral quantitative computerized tomography assessed the bone strength index at the tibial metaphysis (BSI 4) and the polar strength-strain index at the diaphysis (SSI polar 66). The effect of TS on the muscle-bone unit was tested using multiple linear regression. Results: TS had no impact on F-max (p = 0.14); however, a negative effect on bone strength (p <0.001 for BSI 4 and p <0.01 for SSI polar 66) was observed compared with healthy controls. Bone strength was lower in the TS group (by 18%, p <0.01, for BSI 4 and by
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FG - Pediatrie
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Bone
ISSN
8756-3282
e-ISSN
—
Svazek periodika
74
Číslo periodika v rámci svazku
květen
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
160-165
Kód UT WoS článku
000351189400020
EID výsledku v databázi Scopus
2-s2.0-84922436156