Muscle function in Turner syndrome: normal force but decreased power

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F15%3A10294546" target="_blank" >RIV/00216208:11320/15:10294546 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/15:10294546 RIV/00064203:_____/15:10294546

Výsledek na webu

<a href="http://dx.doi.org/10.1111/cen.12518" target="_blank" >http://dx.doi.org/10.1111/cen.12518</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/cen.12518" target="_blank" >10.1111/cen.12518</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Muscle function in Turner syndrome: normal force but decreased power

Popis výsledku v původním jazyce

ObjectiveAlthough hypogonadism and SHOX gene haploinsufficiency likely cause the decreased bone mineral density and increased fracture rate associated with Turner syndrome (TS), the exact mechanism remains unclear. We tested the hypothesis that muscle dysfunction in patients with TS contributes to increased fracture risk. The secondary aim was to determine whether menarche, hormone therapy duration, positive fracture history and genotype influence muscle function parameters in patients with TS. DesignAcross-sectional study was conducted in a single university hospital referral centre between March 2012 and October 2013. PatientsSixty patients with TS (mean age of 13745years) were compared to the control group of 432 healthy girls. MeasurementsA Leonardo Mechanograph((R)) Ground Reaction Force Platform was used to assess muscle force (F-max) by the multiple one-legged hopping test and muscle power (P-max) by the single two-legged jump test. ResultsWhile the F-max was normal (mean weigh

Název v anglickém jazyce

Muscle function in Turner syndrome: normal force but decreased power

Popis výsledku anglicky

ObjectiveAlthough hypogonadism and SHOX gene haploinsufficiency likely cause the decreased bone mineral density and increased fracture rate associated with Turner syndrome (TS), the exact mechanism remains unclear. We tested the hypothesis that muscle dysfunction in patients with TS contributes to increased fracture risk. The secondary aim was to determine whether menarche, hormone therapy duration, positive fracture history and genotype influence muscle function parameters in patients with TS. DesignAcross-sectional study was conducted in a single university hospital referral centre between March 2012 and October 2013. PatientsSixty patients with TS (mean age of 13745years) were compared to the control group of 432 healthy girls. MeasurementsA Leonardo Mechanograph((R)) Ground Reaction Force Platform was used to assess muscle force (F-max) by the multiple one-legged hopping test and muscle power (P-max) by the single two-legged jump test. ResultsWhile the F-max was normal (mean weigh

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FG - Pediatrie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Endocrinology

ISSN

0300-0664

e-ISSN

—

Svazek periodika

82

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

248-253

Kód UT WoS článku

000348575000013

EID výsledku v databázi Scopus

2-s2.0-84921591641