Validation of the Concept of a Common Typical Time of Disease Duration for Hepatocellular Carcinoma Patients Using the Fisher Information Processing of Tumor Imaging Results Combined With Network Phenotyping Strategy Quantification of Individual PatientClinical Profile Patterns

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F15%3A10319697" target="_blank" >RIV/00216208:11320/15:10319697 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1053/j.seminoncol.2015.05.004" target="_blank" >http://dx.doi.org/10.1053/j.seminoncol.2015.05.004</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.seminoncol.2015.05.004" target="_blank" >10.1053/j.seminoncol.2015.05.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Validation of the Concept of a Common Typical Time of Disease Duration for Hepatocellular Carcinoma Patients Using the Fisher Information Processing of Tumor Imaging Results Combined With Network Phenotyping Strategy Quantification of Individual PatientClinical Profile Patterns

Popis výsledku v původním jazyce

A primary goal of current clinical cancer research is the identification of prognostic tumor subtypes. It is increasingly dear that tumor growth depends on both internal tumor factors, and factors that are external to the tumor, such as microenvironment.We recently showed that parameter values alone are less important than the patterns of all patient parameters together for the identification of prognostic subtypes and have identified a network phenotyping strategy method to quantitatively describe thedependency of the tumor on the environment, to characterize hepatocellular carcinoma (HCC) subtypes. We have also shown that information about tumor mass together with patterns of other prognostic factors is related to survival. We now use a different patient cohort to validate this prognostic approach. A main finding is our identification of a common time of total disease duration (MD) for every HCC patient. Clinical prognosis at the time of baseline patient evaluation is then calculab

Název v anglickém jazyce

Validation of the Concept of a Common Typical Time of Disease Duration for Hepatocellular Carcinoma Patients Using the Fisher Information Processing of Tumor Imaging Results Combined With Network Phenotyping Strategy Quantification of Individual PatientClinical Profile Patterns

Popis výsledku anglicky

A primary goal of current clinical cancer research is the identification of prognostic tumor subtypes. It is increasingly dear that tumor growth depends on both internal tumor factors, and factors that are external to the tumor, such as microenvironment.We recently showed that parameter values alone are less important than the patterns of all patient parameters together for the identification of prognostic subtypes and have identified a network phenotyping strategy method to quantitatively describe thedependency of the tumor on the environment, to characterize hepatocellular carcinoma (HCC) subtypes. We have also shown that information about tumor mass together with patterns of other prognostic factors is related to survival. We now use a different patient cohort to validate this prognostic approach. A main finding is our identification of a common time of total disease duration (MD) for every HCC patient. Clinical prognosis at the time of baseline patient evaluation is then calculab

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BB - Aplikovaná statistika, operační výzkum

OECD FORD obor

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Projekt

<a href="/cs/project/LL1201" target="_blank" >LL1201: Komplexní Struktury: Regularita v Kombinatorice a Diskrétní Matematice</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Seminars in Oncology

ISSN

0093-7754

e-ISSN

—

Svazek periodika

42

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

672-678

Kód UT WoS článku

000360782200015

EID výsledku v databázi Scopus

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