Enantiomeric Excess Dependent Splitting of NMR Signal through Dynamic Chiral Inversion and Coligand Exchange in a Coordination Complex

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F20%3A10420639" target="_blank" >RIV/00216208:11320/20:10420639 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Hj5-Sqcrh0" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Hj5-Sqcrh0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.jpclett.0c02284" target="_blank" >10.1021/acs.jpclett.0c02284</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Enantiomeric Excess Dependent Splitting of NMR Signal through Dynamic Chiral Inversion and Coligand Exchange in a Coordination Complex

Popis výsledku v původním jazyce

Nuclear magnetic resonance (NMR) spectroscopy cannot be used to discriminate enantiomers, and NMR resonances of enantiomeric mixtures are generally not affected by enantiomeric excess (ee). Here, we report that a coordination complex (L.2Zn.3C), where L is a salen-like prochiral ligand and C is an exchangeable acetate coligand, exhibits symmetrical splitting of one of the H-1 NMR resonances of L with the degree of splitting linearly proportional to ee of the chiral guest coligand C, 2-phenoxypropionic acid. Despite the well-defined chirality in the crystal structure of L.2Zn.3C, concurrent fast chiral inversion and coligand exchange in solution renders L.2Zn.3C the primary example of prochiral solvating agent (pro-CSA) based on a coordination complex. Notably, the NMR resonances remain split even in dilute solution due to the lack of chiral guest dissociation in the coligand exchange system. This work provides new insights into chiral transfer events in metal-ligand complexes.

Název v anglickém jazyce

Enantiomeric Excess Dependent Splitting of NMR Signal through Dynamic Chiral Inversion and Coligand Exchange in a Coordination Complex

Popis výsledku anglicky

Nuclear magnetic resonance (NMR) spectroscopy cannot be used to discriminate enantiomers, and NMR resonances of enantiomeric mixtures are generally not affected by enantiomeric excess (ee). Here, we report that a coordination complex (L.2Zn.3C), where L is a salen-like prochiral ligand and C is an exchangeable acetate coligand, exhibits symmetrical splitting of one of the H-1 NMR resonances of L with the degree of splitting linearly proportional to ee of the chiral guest coligand C, 2-phenoxypropionic acid. Despite the well-defined chirality in the crystal structure of L.2Zn.3C, concurrent fast chiral inversion and coligand exchange in solution renders L.2Zn.3C the primary example of prochiral solvating agent (pro-CSA) based on a coordination complex. Notably, the NMR resonances remain split even in dilute solution due to the lack of chiral guest dissociation in the coligand exchange system. This work provides new insights into chiral transfer events in metal-ligand complexes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Physical Chemistry Letters

ISSN

1948-7185

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

19

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

8164-8169

Kód UT WoS článku

000577152900034

EID výsledku v databázi Scopus

2-s2.0-85092682467