Quasi-neutral evolution in populations under small demographic fluctuations

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F22%3A10456713" target="_blank" >RIV/00216208:11320/22:10456713 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=dtJyqT-vXf" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=dtJyqT-vXf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jtbi.2022.111040" target="_blank" >10.1016/j.jtbi.2022.111040</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Quasi-neutral evolution in populations under small demographic fluctuations

Popis výsledku v původním jazyce

We study an eco-evolutionary dynamics in finite populations of two haploid asexually reproducing allelic types. We focus on the quasi-neutral case when individual types differ only in their intrinsic birth and death rates but have the same expected lifetime reproductive output. We assume that the population size can fluctuate stochastically. We solve the Kolmogorov forward equation in the population whose size fluctuates only minimally and show that the fixation probability is decreasing with the increasing turnover rate. We also show that when the mutant&apos;s turnover is small enough, selection favors the mutant replacing residents. Similarly, when the turnover is high enough, selection opposes the replacement. This basic result has previously been demonstrated numerically for the contact process and shown analytically for the Moran process; the current paper extends this analysis to provide an analytical proof for the contact process. We also demonstrate numerically that our results extend for general fluctuating populations and beyond the quasi-neutral case. (C) 2022 Elsevier Ltd. All rights reserved.

Název v anglickém jazyce

Quasi-neutral evolution in populations under small demographic fluctuations

Popis výsledku anglicky

We study an eco-evolutionary dynamics in finite populations of two haploid asexually reproducing allelic types. We focus on the quasi-neutral case when individual types differ only in their intrinsic birth and death rates but have the same expected lifetime reproductive output. We assume that the population size can fluctuate stochastically. We solve the Kolmogorov forward equation in the population whose size fluctuates only minimally and show that the fixation probability is decreasing with the increasing turnover rate. We also show that when the mutant&apos;s turnover is small enough, selection favors the mutant replacing residents. Similarly, when the turnover is high enough, selection opposes the replacement. This basic result has previously been demonstrated numerically for the contact process and shown analytically for the Moran process; the current paper extends this analysis to provide an analytical proof for the contact process. We also demonstrate numerically that our results extend for general fluctuating populations and beyond the quasi-neutral case. (C) 2022 Elsevier Ltd. All rights reserved.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10101 - Pure mathematics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Theoretical Biology

ISSN

0022-5193

e-ISSN

1095-8541

Svazek periodika

538

Číslo periodika v rámci svazku

2022

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

111040

Kód UT WoS článku

000814479000010

EID výsledku v databázi Scopus

2-s2.0-85123939845