Změny imunofluorescenčního barvení molekul ECM ve spinálních gangliích potkana po chronické kompresi periferního nervu.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F04%3A00010570" target="_blank" >RIV/00216224:14110/04:00010570 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Changes of immunofluorescence staining for ECM molecules in the rat dorsal root ganglia following chronic compression of the peripheral nerve

Popis výsledku v původním jazyce

The units of neuronal body-satellite cells in the dorsal root ganglia (DRG) are surrounded by the basal lamina and extracellular matrix (ECM) produced by the satellite cells. The neurons shift from normal maintenance and neurotransmission toward survivaland regeneration after axonal injury. However, scarce information is available on reaction of satellite cells following axotomy. The present experiments demonstrate changes of immunofluorescence staining for laminin-1, chondroitin sulfate proteoglycan (CSP), tenascin (TEN), thrombospondin (THS) and fibronectin (FN) in the DRG after intercostal nerve ligation. Twenty adult rats were deeply anesthetized and left intercostal nerves (8-12) were ligated by 6-0 Mersilk thread. Animals were allowed to survivefor 1 or 2 weeks. The corresponding DRG (Th8-12) of both sides were removed and immersed in Zamboni fixation. Intact DRG (Th8-12) were removed and fixed from other 4 rats. Longitudinal cryostat sections (12 ľm) through ipsilateral, contr

Název v anglickém jazyce

Changes of immunofluorescence staining for ECM molecules in the rat dorsal root ganglia following chronic compression of the peripheral nerve

Popis výsledku anglicky

The units of neuronal body-satellite cells in the dorsal root ganglia (DRG) are surrounded by the basal lamina and extracellular matrix (ECM) produced by the satellite cells. The neurons shift from normal maintenance and neurotransmission toward survivaland regeneration after axonal injury. However, scarce information is available on reaction of satellite cells following axotomy. The present experiments demonstrate changes of immunofluorescence staining for laminin-1, chondroitin sulfate proteoglycan (CSP), tenascin (TEN), thrombospondin (THS) and fibronectin (FN) in the DRG after intercostal nerve ligation. Twenty adult rats were deeply anesthetized and left intercostal nerves (8-12) were ligated by 6-0 Mersilk thread. Animals were allowed to survivefor 1 or 2 weeks. The corresponding DRG (Th8-12) of both sides were removed and immersed in Zamboni fixation. Intact DRG (Th8-12) were removed and fixed from other 4 rats. Longitudinal cryostat sections (12 ľm) through ipsilateral, contr

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

—

Projekt

<a href="/cs/project/GA309%2F03%2F1199" target="_blank" >GA309/03/1199: Změny v satelitních gliových buňkách a jejich extracelulární matrix po axotomii - podmínky pro tvorbu sympatických kolaterál ve spinálních gangliích ?</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Molecular Histology

ISSN

1567-2379

e-ISSN

—

Svazek periodika

35

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

178-178

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—