Ischemicko-reperfůzní počkození myokardu: od kalciového paradoxu k volným radikálům

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Ischemic-reperfusion injury of myocardium: from calcium paradox to free radicals

Popis výsledku v původním jazyce

Cardiac ischemia has been extensively studied for last several decades. This adverse state of myocardium is very important clinically as numerous patients in developed countries suffer from ischemic heart disease with all its consequences (e.g. myocardial infarction). Later, the crucial role of reperfusion ? the period following the successful blood flow recovery, often caused by therapeutic interventions ? has been widely investigated. Still, two mainstreams can be traced in the literature concerning ischemic-reperfusion injury of myocardium. One group of researchers focuses on the calcium overload phenomenon, the others study the role of reactive oxygen species (ROS) during ischemia and reperfusion. More recently, the terms preconditioning and postconditioning have been introduced and these events are intensely studied. The methods used for studying both electrical and mechanical events on the heart are of various origin and elaborateness. In our laboratory, the registration of monop

Název v anglickém jazyce

Ischemic-reperfusion injury of myocardium: from calcium paradox to free radicals

Popis výsledku anglicky

Cardiac ischemia has been extensively studied for last several decades. This adverse state of myocardium is very important clinically as numerous patients in developed countries suffer from ischemic heart disease with all its consequences (e.g. myocardial infarction). Later, the crucial role of reperfusion ? the period following the successful blood flow recovery, often caused by therapeutic interventions ? has been widely investigated. Still, two mainstreams can be traced in the literature concerning ischemic-reperfusion injury of myocardium. One group of researchers focuses on the calcium overload phenomenon, the others study the role of reactive oxygen species (ROS) during ischemia and reperfusion. More recently, the terms preconditioning and postconditioning have been introduced and these events are intensely studied. The methods used for studying both electrical and mechanical events on the heart are of various origin and elaborateness. In our laboratory, the registration of monop

Druh

D - Stať ve sborníku

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

XX. Biochemický zjazd

ISBN

80-969532-6-5

ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

124

Název nakladatele

Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences

Místo vydání

Bratislava

Místo konání akce

Piešťany

Datum konání akce

12. 9. 2006

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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