Je možno detekovat vývoj citlivosti baroreflexu u člověka ve věku 11 až 20 let?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00018695" target="_blank" >RIV/00216224:14110/06:00018695 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/06:#0000323

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?

Popis výsledku v původním jazyce

The aim of the study was to determine changes of baroreflex sensitivity (BRS/BRSf) in humans between 11 and 20 years of age. Beat-by-beat values of inter-beat intervals (IBI) or heart rate, and systolic and diastolic blood pressures were measured for 5 min in 415 healthy subjects. BRS did not correlate with age, but BRSf significantly decreased (p&lt;0.001). BRS correlated with mean IBI (p&lt;0.001), but BRSf was IBI-independent. Results of multiregression equations were: BRS=1.37-0.56*age+0.02*IBI (p&lt;0.001 for BRS vs. age and for BRS vs. IBI); BRSf=34.74?0.97*age-0.001*IBI (p&lt;0.001 only for BRS vs. age). The limits of BRS: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.7, and limits for BRSf: 5th percentile - 8.5 mHz/mmHg; 50th - 16.4; 95th- 33.6. Conclusion: IBI-dependent BRS was unchanged in the particular age groups, but the standardization of BRS on IBI was decreased with age. BRSf was IBI-independent and better reflected the development of the baroreflex sensitivity.

Název v anglickém jazyce

Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?

Popis výsledku anglicky

The aim of the study was to determine changes of baroreflex sensitivity (BRS/BRSf) in humans between 11 and 20 years of age. Beat-by-beat values of inter-beat intervals (IBI) or heart rate, and systolic and diastolic blood pressures were measured for 5 min in 415 healthy subjects. BRS did not correlate with age, but BRSf significantly decreased (p&lt;0.001). BRS correlated with mean IBI (p&lt;0.001), but BRSf was IBI-independent. Results of multiregression equations were: BRS=1.37-0.56*age+0.02*IBI (p&lt;0.001 for BRS vs. age and for BRS vs. IBI); BRSf=34.74?0.97*age-0.001*IBI (p&lt;0.001 only for BRS vs. age). The limits of BRS: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.7, and limits for BRSf: 5th percentile - 8.5 mHz/mmHg; 50th - 16.4; 95th- 33.6. Conclusion: IBI-dependent BRS was unchanged in the particular age groups, but the standardization of BRS on IBI was decreased with age. BRSf was IBI-independent and better reflected the development of the baroreflex sensitivity.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

<a href="/cs/project/NR8006" target="_blank" >NR8006: Autonomní oběhové funkce, funkce myokardu a kardiorespirační funkce u dětí a adolescentů po léčbě zhoubného nádoru</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Canadian Journal of Physiology and Pharmacology

ISSN

1205-7541

e-ISSN

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Svazek periodika

84

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

CA - Kanada

Počet stran výsledku

9

Strana od-do

1275-1283

Kód UT WoS článku

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EID výsledku v databázi Scopus

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