Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00051164" target="_blank" >RIV/00216224:14110/09:00051164 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.seizure.2008.10.012" target="_blank" >http://dx.doi.org/10.1016/j.seizure.2008.10.012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.seizure.2008.10.012" target="_blank" >10.1016/j.seizure.2008.10.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.

Popis výsledku v původním jazyce

We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up64.4% of patients were responders, 15.5% experienced &gt;= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole grou

Název v anglickém jazyce

Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.

Popis výsledku anglicky

We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up64.4% of patients were responders, 15.5% experienced &gt;= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole grou

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Seizure

ISSN

1059-1311

e-ISSN

—

Svazek periodika

18

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

269-274

Kód UT WoS článku

000265465000007

EID výsledku v databázi Scopus

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