B-cell activating factor (BAFF) ? a new factor linking immunity to diet?
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060623" target="_blank" >RIV/00216224:14110/12:00060623 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.2478/s11536-011-0153-7" target="_blank" >http://dx.doi.org/10.2478/s11536-011-0153-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/s11536-011-0153-7" target="_blank" >10.2478/s11536-011-0153-7</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
B-cell activating factor (BAFF) ? a new factor linking immunity to diet?
Popis výsledku v původním jazyce
B cell activation factor (BAFF) is a recently discovered member of the TNF ligand superfamily secreted by adipocytes, previously linked to autoimmune and lymphoproliferative disease. The aim of this study was to investigate the relationship between BAFFplasma levels and the non-modified, usual dietary composition as well as obesity-related anthropometric parameters in a cohort of 58 obese and non-obese Central-European Caucasian individuals. We found that BAFF had an independent predictive role for percentage of body fat; moreover, BAFF levels were correlated with waist and hip circumference. BAFF plasma levels were also significantly correlated with investigated dietary composition based on the 7-day food records, as the BAFF levels correlated with the percentage of energy derived from the carbohydrates and with energy derived from the dietary fat. Our results suggest that BAFF may play a role in linking the immune status and metabolic response to diet.
Název v anglickém jazyce
B-cell activating factor (BAFF) ? a new factor linking immunity to diet?
Popis výsledku anglicky
B cell activation factor (BAFF) is a recently discovered member of the TNF ligand superfamily secreted by adipocytes, previously linked to autoimmune and lymphoproliferative disease. The aim of this study was to investigate the relationship between BAFFplasma levels and the non-modified, usual dietary composition as well as obesity-related anthropometric parameters in a cohort of 58 obese and non-obese Central-European Caucasian individuals. We found that BAFF had an independent predictive role for percentage of body fat; moreover, BAFF levels were correlated with waist and hip circumference. BAFF plasma levels were also significantly correlated with investigated dietary composition based on the 7-day food records, as the BAFF levels correlated with the percentage of energy derived from the carbohydrates and with energy derived from the dietary fat. Our results suggest that BAFF may play a role in linking the immune status and metabolic response to diet.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FP - Ostatní lékařské obory
OECD FORD obor
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Návaznosti výsledku
Projekt
—
Návaznosti
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Central European Journal of Medicine
ISSN
1895-1058
e-ISSN
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Svazek periodika
7
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
PL - Polská republika
Počet stran výsledku
9
Strana od-do
275-283
Kód UT WoS článku
000304396200001
EID výsledku v databázi Scopus
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