Functional neuroanatomy of vocalization in patients with Parkinson's disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00068876" target="_blank" >RIV/00216224:14110/12:00068876 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jns.2011.10.020" target="_blank" >http://dx.doi.org/10.1016/j.jns.2011.10.020</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jns.2011.10.020" target="_blank" >10.1016/j.jns.2011.10.020</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Functional neuroanatomy of vocalization in patients with Parkinson's disease

Popis výsledku v původním jazyce

In Parkinson's disease (PD) both speech production and self-monitoring of voiced speech are altered. Methods: In our previous study we used functional magnetic resonance imaging (fMRI) to examine which brain areas are involved in overt reading in nine female PD patients (mean age 66.0 +/- 11.6 years) compared with eight age-matched healthy female controls (mean age 62.2 years +/- 12.3). Here we performed the posthoc seed-based functional connectivity analysis of our data to assess the functional connectivity between the periaqueductal gray matter (PAG; i.e. the core subcortical structure involved in human vocalization) and other brain regions in the same groups of PD patients and controls. Results: In PD patients as compared with controls we observed increased connectivity between PAG and basal ganglia, posterior superior temporal gyrus, supramarginal and fusiform gyri and inferior parietal lobule on the right side.

Název v anglickém jazyce

Functional neuroanatomy of vocalization in patients with Parkinson's disease

Popis výsledku anglicky

In Parkinson's disease (PD) both speech production and self-monitoring of voiced speech are altered. Methods: In our previous study we used functional magnetic resonance imaging (fMRI) to examine which brain areas are involved in overt reading in nine female PD patients (mean age 66.0 +/- 11.6 years) compared with eight age-matched healthy female controls (mean age 62.2 years +/- 12.3). Here we performed the posthoc seed-based functional connectivity analysis of our data to assess the functional connectivity between the periaqueductal gray matter (PAG; i.e. the core subcortical structure involved in human vocalization) and other brain regions in the same groups of PD patients and controls. Results: In PD patients as compared with controls we observed increased connectivity between PAG and basal ganglia, posterior superior temporal gyrus, supramarginal and fusiform gyri and inferior parietal lobule on the right side.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF THE NEUROLOGICAL SCIENCES

ISSN

0022-510X

e-ISSN

—

Svazek periodika

313

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

7-12

Kód UT WoS článku

000299978800002

EID výsledku v databázi Scopus

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