Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00073699" target="_blank" >RIV/00216224:14110/14:00073699 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jab.2014.01.002" target="_blank" >http://dx.doi.org/10.1016/j.jab.2014.01.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jab.2014.01.002" target="_blank" >10.1016/j.jab.2014.01.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

Popis výsledku v původním jazyce

Antibacterial activity of silver nanoparticles is widely known and used. The effect of application of therapeutical ultrasonic field in the presence of silver nanoparticles &lt;100 nm was examined on human ovarian carcinoma cell A2780. The cell's viability was examined by MTT assay and by life-time microscopy. The presence of nanoparticles in the cell was examined by using electron transmission microscopy. Experimental results indicate a significant decrease of viability of cell, which was affected by the combined action of ultrasound field and silver nanoparticles, compared to the separate exposure of silver nanoparticles or ultrasonic field. The experiments showed a significant effect of succession of application of these two factors. The presence ofnanoparticles inside cells after incubation was showed. The results show the possibility of using of ultrasonic field as a factor that can significantly affect cell viability in the presence of silver nanoparticles.

Název v anglickém jazyce

Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

Popis výsledku anglicky

Antibacterial activity of silver nanoparticles is widely known and used. The effect of application of therapeutical ultrasonic field in the presence of silver nanoparticles &lt;100 nm was examined on human ovarian carcinoma cell A2780. The cell's viability was examined by MTT assay and by life-time microscopy. The presence of nanoparticles in the cell was examined by using electron transmission microscopy. Experimental results indicate a significant decrease of viability of cell, which was affected by the combined action of ultrasound field and silver nanoparticles, compared to the separate exposure of silver nanoparticles or ultrasonic field. The experiments showed a significant effect of succession of application of these two factors. The presence ofnanoparticles inside cells after incubation was showed. The results show the possibility of using of ultrasonic field as a factor that can significantly affect cell viability in the presence of silver nanoparticles.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

<a href="/cs/project/GP13-04408P" target="_blank" >GP13-04408P: Ovlivnění nádorových buněk kombinovaným působením nanočástic a ultrazvukového pole</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Svazek periodika

12

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

137-145

Kód UT WoS článku

000340867600002

EID výsledku v databázi Scopus

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