Cytomegalovirus Disease in Patients with Common Variable Immunodeficiency: Three Case Reports

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00074832" target="_blank" >RIV/00216224:14110/14:00074832 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/14:10227362 RIV/00179906:_____/14:10227362 RIV/00159816:_____/14:00061421

Výsledek na webu

<a href="http://dx.doi.org/10.1159/000355957" target="_blank" >http://dx.doi.org/10.1159/000355957</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000355957" target="_blank" >10.1159/000355957</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cytomegalovirus Disease in Patients with Common Variable Immunodeficiency: Three Case Reports

Popis výsledku v původním jazyce

Common variable immunodeficiency (CVID) is the most frequent clinically relevant primary immunodeficiency and shows enormous heterogeneity in clinical presentation. Despite clinical immunodeficiency, opportunistic infections are not a typical manifestation of CVID. A retrospective study of 32 patients followed up for 335 patient-years was performed to determine the frequency of cytomegalovirus (CMV) disease. Symptomatic CMV infection was documented in 3 CVID patients. Patients No. 1 and 2 suffered fromCMV pneumonia, with complications due to atypical mycobacteriosis in patient No. 1. Patient No. 3 suffered from CMV enteritis. A history of cancer and chronic hepatitis C infection (patient No. 1), immunosuppressive therapy for interstitial lung disease(patient No. 2) and serious enteropathy complicated with malnutrition (patient No. 3) may have contributed to the complications despite only mild abnormalities in T-cell subpopulations.

Název v anglickém jazyce

Cytomegalovirus Disease in Patients with Common Variable Immunodeficiency: Three Case Reports

Popis výsledku anglicky

Common variable immunodeficiency (CVID) is the most frequent clinically relevant primary immunodeficiency and shows enormous heterogeneity in clinical presentation. Despite clinical immunodeficiency, opportunistic infections are not a typical manifestation of CVID. A retrospective study of 32 patients followed up for 335 patient-years was performed to determine the frequency of cytomegalovirus (CMV) disease. Symptomatic CMV infection was documented in 3 CVID patients. Patients No. 1 and 2 suffered fromCMV pneumonia, with complications due to atypical mycobacteriosis in patient No. 1. Patient No. 3 suffered from CMV enteritis. A history of cancer and chronic hepatitis C infection (patient No. 1), immunosuppressive therapy for interstitial lung disease(patient No. 2) and serious enteropathy complicated with malnutrition (patient No. 3) may have contributed to the complications despite only mild abnormalities in T-cell subpopulations.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International archives of allergy and immunology

ISSN

1018-2438

e-ISSN

—

Svazek periodika

163

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

6

Strana od-do

69-74

Kód UT WoS článku

000329603200012

EID výsledku v databázi Scopus

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