Antitumour activities of sanguinarine and related alkaloids

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00074837" target="_blank" >RIV/00216224:14110/14:00074837 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11101-013-9290-8" target="_blank" >http://dx.doi.org/10.1007/s11101-013-9290-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11101-013-9290-8" target="_blank" >10.1007/s11101-013-9290-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antitumour activities of sanguinarine and related alkaloids

Popis výsledku v původním jazyce

Sanguinarine is a best-known member of a relatively small group of quaternary benzo[c]phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae and, to a limited extent, in some species of the families Fumariaceae and Rutaceae. From a medical perspective, QBAs have many important properties. In addition to antitumour activity, they display antimicrobial, antifungal and anti-inflammatory effects. They may interact with many targets, such as DNA and microtubules, and they modify the activities of a wide variety of enzymes. This review summarises the current state of knowledge about the properties of QBAs that are important for their potential use in anticancer therapy.

Název v anglickém jazyce

Antitumour activities of sanguinarine and related alkaloids

Popis výsledku anglicky

Sanguinarine is a best-known member of a relatively small group of quaternary benzo[c]phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae and, to a limited extent, in some species of the families Fumariaceae and Rutaceae. From a medical perspective, QBAs have many important properties. In addition to antitumour activity, they display antimicrobial, antifungal and anti-inflammatory effects. They may interact with many targets, such as DNA and microtubules, and they modify the activities of a wide variety of enzymes. This review summarises the current state of knowledge about the properties of QBAs that are important for their potential use in anticancer therapy.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Phytochemistry reviews

ISSN

1568-7767

e-ISSN

—

Svazek periodika

13

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

18

Strana od-do

51-68

Kód UT WoS článku

000331818000004

EID výsledku v databázi Scopus

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