Clinical picture and treatment of 2212 patients with common variable immunodeficiency

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077279" target="_blank" >RIV/00216224:14110/14:00077279 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/14:10292987 RIV/00159816:_____/14:00061364 RIV/00064203:_____/14:10292987

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jaci.2013.12.1077" target="_blank" >http://dx.doi.org/10.1016/j.jaci.2013.12.1077</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jaci.2013.12.1077" target="_blank" >10.1016/j.jaci.2013.12.1077</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Clinical picture and treatment of 2212 patients with common variable immunodeficiency

Popis výsledku v původním jazyce

Background: Common variable immunodeficiency (CVID) is an antibody deficiency with an equal sex distribution and a high variability in clinical presentation. The main features include respiratory tract infections and their associated complications, enteropathy, autoimmunity, and lymphoproliferative disorders. Objective: This study analyzes the clinical presentation, association between clinical features, and differences and effects of immunoglobulin treatment in Europe. Methods: Data on 2212 patients with CVID from 28 medical centers contributing to the European Society for Immunodeficiencies Database were analyzed retrospectively. Results: Early disease onset (&lt; 10 years) was very frequent in our cohort (33.7%), especially in male subjects (39.8%).Male subjects with early-onset CVID were more prone to pneumonia and less prone to other complications suggesting a distinct disease entity.

Název v anglickém jazyce

Clinical picture and treatment of 2212 patients with common variable immunodeficiency

Popis výsledku anglicky

Background: Common variable immunodeficiency (CVID) is an antibody deficiency with an equal sex distribution and a high variability in clinical presentation. The main features include respiratory tract infections and their associated complications, enteropathy, autoimmunity, and lymphoproliferative disorders. Objective: This study analyzes the clinical presentation, association between clinical features, and differences and effects of immunoglobulin treatment in Europe. Methods: Data on 2212 patients with CVID from 28 medical centers contributing to the European Society for Immunodeficiencies Database were analyzed retrospectively. Results: Early disease onset (&lt; 10 years) was very frequent in our cohort (33.7%), especially in male subjects (39.8%).Male subjects with early-onset CVID were more prone to pneumonia and less prone to other complications suggesting a distinct disease entity.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ISSN

0091-6749

e-ISSN

—

Svazek periodika

134

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

22

Strana od-do

"116"-"+"

Kód UT WoS článku

000338930300016

EID výsledku v databázi Scopus

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