gamma-Fe2O3 Nanoparticles Covered with Glutathione-Modified Quantum Dots as a Fluorescent Nanotransporter

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00078584" target="_blank" >RIV/00216224:14110/14:00078584 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/14:00230475

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s10337-014-2732-7" target="_blank" >http://dx.doi.org/10.1007/s10337-014-2732-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10337-014-2732-7" target="_blank" >10.1007/s10337-014-2732-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

gamma-Fe2O3 Nanoparticles Covered with Glutathione-Modified Quantum Dots as a Fluorescent Nanotransporter

Popis výsledku v původním jazyce

The present paper describes the synthesis, characterization, and utilization of multi-functional magnetic conjugates that integrate optical and magnetic properties in a single structure for use in many biomedical applications. Spontaneous interaction with eukaryotic cell membrane (HEK-239 cell culture) was determined using fluorescence microscopy, and fluorescence analyses. Both, differences in excitation, and emission wavelength were observed, caused by glutathione intake by cells, resulting in disintegration of core-shell structure of quantum dots, as well as adhesion of conjugate onto cell surface. When compared with quantum dots fluorescent properties, HEK-239 cells with incorporated nanoconjugate exhibited two excitation maxima (lambda (ex) = 430and 390 nm). Simultaneously, application of ideal lambda (ex) for quantum dots (lambda (ex) = 430 nm), resulted in two emission maxima (lambda = 740 and 750 nm).

Název v anglickém jazyce

gamma-Fe2O3 Nanoparticles Covered with Glutathione-Modified Quantum Dots as a Fluorescent Nanotransporter

Popis výsledku anglicky

The present paper describes the synthesis, characterization, and utilization of multi-functional magnetic conjugates that integrate optical and magnetic properties in a single structure for use in many biomedical applications. Spontaneous interaction with eukaryotic cell membrane (HEK-239 cell culture) was determined using fluorescence microscopy, and fluorescence analyses. Both, differences in excitation, and emission wavelength were observed, caused by glutathione intake by cells, resulting in disintegration of core-shell structure of quantum dots, as well as adhesion of conjugate onto cell surface. When compared with quantum dots fluorescent properties, HEK-239 cells with incorporated nanoconjugate exhibited two excitation maxima (lambda (ex) = 430and 390 nm). Simultaneously, application of ideal lambda (ex) for quantum dots (lambda (ex) = 430 nm), resulted in two emission maxima (lambda = 740 and 750 nm).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chromatographia

ISSN

0009-5893

e-ISSN

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Svazek periodika

77

Číslo periodika v rámci svazku

21-22

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

9

Strana od-do

1415-1423

Kód UT WoS článku

000345004800002

EID výsledku v databázi Scopus

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