Anti-Gal IgM, IgA and IgG Natural Antibodies in Childhood
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082841" target="_blank" >RIV/00216224:14110/15:00082841 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.imlet.2015.02.001" target="_blank" >http://dx.doi.org/10.1016/j.imlet.2015.02.001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.imlet.2015.02.001" target="_blank" >10.1016/j.imlet.2015.02.001</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Anti-Gal IgM, IgA and IgG Natural Antibodies in Childhood
Popis výsledku v původním jazyce
The target for the most abundant xenoreactive natural antibodies in humans is the a-Gal epitope. Anti-Gal could provide natural immune defense against pathogens that express the a-Gal epitope. Anti-Gal natural antibodies are usually studied in adult individuals. Data demonstrating the incidence and concentration of anti-Gal natural antibodies in childhood are in short supply and incomplete. In the present study we prospectively quantified anti-Gal IgM, IgA and IgG levels in different age groups of children from delivery to 24 months of age and compared these levels to the level of these antibodies in their respective mothers. Measurement of anti-Gal antibodies may broaden the spectrum of specific antibodies that are available for determination of specific antibody responses in physiological and pathological conditions in children. Plasma was collected from umbilical cord blood of full term newborn, from blood of infants at age 6, 12 and 24 months and from their respective mothers at ti
Název v anglickém jazyce
Anti-Gal IgM, IgA and IgG Natural Antibodies in Childhood
Popis výsledku anglicky
The target for the most abundant xenoreactive natural antibodies in humans is the a-Gal epitope. Anti-Gal could provide natural immune defense against pathogens that express the a-Gal epitope. Anti-Gal natural antibodies are usually studied in adult individuals. Data demonstrating the incidence and concentration of anti-Gal natural antibodies in childhood are in short supply and incomplete. In the present study we prospectively quantified anti-Gal IgM, IgA and IgG levels in different age groups of children from delivery to 24 months of age and compared these levels to the level of these antibodies in their respective mothers. Measurement of anti-Gal antibodies may broaden the spectrum of specific antibodies that are available for determination of specific antibody responses in physiological and pathological conditions in children. Plasma was collected from umbilical cord blood of full term newborn, from blood of infants at age 6, 12 and 24 months and from their respective mothers at ti
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EC - Imunologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/7E08062" target="_blank" >7E08062: Pathophysiology and Natural Course of Primary Antibody Deficiency (PAD) Syndromes</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Immunology Letters
ISSN
0165-2478
e-ISSN
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Svazek periodika
164
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
4
Strana od-do
40-43
Kód UT WoS článku
000351801500006
EID výsledku v databázi Scopus
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