Increasing procoagulant activity of circulating microparticles in patients with Philadelphia-negative myeloproliferative neoplasms: a single-centre experience
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083018" target="_blank" >RIV/00216224:14110/15:00083018 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/65269705:_____/15:00063096
Výsledek na webu
<a href="http://dx.doi.org/10.1097/MBC.0000000000000293" target="_blank" >http://dx.doi.org/10.1097/MBC.0000000000000293</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/MBC.0000000000000293" target="_blank" >10.1097/MBC.0000000000000293</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Increasing procoagulant activity of circulating microparticles in patients with Philadelphia-negative myeloproliferative neoplasms: a single-centre experience
Popis výsledku v původním jazyce
Microparticles are small membrane fragments with dimension between 0.1 and 1 mu m, which are released during cell activation or apoptosis, exposing the phospholipid phosphatidylserine and membrane antigens typical for cellular origin. Philadelphia-negative myeloproliferative neoplasms (MPNs) are characterized by an increased risk of thrombosis. Data from literature suggest an association between thrombosis and the procoagulant activity of microparticles. Association between the procoagulant activity ofmicroparticles and the incidence of thrombosis was assesed in a group of 126 patients with Philadelphia-negative MPNs. Measurement of microparticles procoagulant activity was performed using a functional assay, namely the Zymuphen MP-activity (Hyphen Biomed, Neuville-sur-oise, France). A total of 539 samples were analysed within this group of patients, regardless of patients' state of health.
Název v anglickém jazyce
Increasing procoagulant activity of circulating microparticles in patients with Philadelphia-negative myeloproliferative neoplasms: a single-centre experience
Popis výsledku anglicky
Microparticles are small membrane fragments with dimension between 0.1 and 1 mu m, which are released during cell activation or apoptosis, exposing the phospholipid phosphatidylserine and membrane antigens typical for cellular origin. Philadelphia-negative myeloproliferative neoplasms (MPNs) are characterized by an increased risk of thrombosis. Data from literature suggest an association between thrombosis and the procoagulant activity of microparticles. Association between the procoagulant activity ofmicroparticles and the incidence of thrombosis was assesed in a group of 126 patients with Philadelphia-negative MPNs. Measurement of microparticles procoagulant activity was performed using a functional assay, namely the Zymuphen MP-activity (Hyphen Biomed, Neuville-sur-oise, France). A total of 539 samples were analysed within this group of patients, regardless of patients' state of health.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FD - Onkologie a hematologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
BLOOD COAGULATION & FIBRINOLYSIS
ISSN
0957-5235
e-ISSN
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Svazek periodika
26
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
448-453
Kód UT WoS článku
000353828800016
EID výsledku v databázi Scopus
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