Salivary neopterin concentrations in patients with cancer of the oral cavity
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00093166" target="_blank" >RIV/00216224:14110/16:00093166 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15110/16:33160444
Výsledek na webu
<a href="http://dx.doi.org/10.1515/pterid-2015-0017" target="_blank" >http://dx.doi.org/10.1515/pterid-2015-0017</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/pterid-2015-0017" target="_blank" >10.1515/pterid-2015-0017</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Salivary neopterin concentrations in patients with cancer of the oral cavity
Popis výsledku v původním jazyce
Tumors of the oral cavity are relatively common malignancies with a poor prognosis. Use of both prognostic and predictive biomarkers in saliva represents one approach to improve the management of patients with these cancers. The aim of the present study was to measure salivary neopterin concentrations before and after surgery in patients with oropharyngeal cancer to assess potential use as a biomarker in clinical practice. Salivary neopterin concentration was determined before and after surgery in 16 patients treated for oropharyngeal cancer and compared with 15 healthy volunteers. Salivary neopterin concentrations were significantly higher in patients before surgery compared to the healthy controls. After the surgery, neopterin concentrations decreased significantly, and concentrations in patients and controls were comparable. A significant correlation was observed between the sum of the Community Periodontal Index of Treatment Needs values and salivary neopterin concentrations.
Název v anglickém jazyce
Salivary neopterin concentrations in patients with cancer of the oral cavity
Popis výsledku anglicky
Tumors of the oral cavity are relatively common malignancies with a poor prognosis. Use of both prognostic and predictive biomarkers in saliva represents one approach to improve the management of patients with these cancers. The aim of the present study was to measure salivary neopterin concentrations before and after surgery in patients with oropharyngeal cancer to assess potential use as a biomarker in clinical practice. Salivary neopterin concentration was determined before and after surgery in 16 patients treated for oropharyngeal cancer and compared with 15 healthy volunteers. Salivary neopterin concentrations were significantly higher in patients before surgery compared to the healthy controls. After the surgery, neopterin concentrations decreased significantly, and concentrations in patients and controls were comparable. A significant correlation was observed between the sum of the Community Periodontal Index of Treatment Needs values and salivary neopterin concentrations.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CE - Biochemie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Pteridines
ISSN
0933-4807
e-ISSN
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Svazek periodika
27
Číslo periodika v rámci svazku
3-4
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
6
Strana od-do
53-58
Kód UT WoS článku
000390413200001
EID výsledku v databázi Scopus
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