Anterior thalamic deep brain stimulation in epilepsy and persistent psychiatric side effects following discontinuation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F19%3A00108623" target="_blank" >RIV/00216224:14110/19:00108623 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/19:00071777

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S2589986419301297?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2589986419301297?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ebr.2019.100344" target="_blank" >10.1016/j.ebr.2019.100344</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Anterior thalamic deep brain stimulation in epilepsy and persistent psychiatric side effects following discontinuation

Popis výsledku v původním jazyce

We report a case of a patient with drug-resistant epilepsy treated with deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS). The patient developed psychiatric side effects (PSEs), namely irritability, hostility, aggressiveness, and paranoia, after implantation and stimulation initiation. The stimulation was discontinued and the PSEs were mitigated, but the patient did not return to her pre-implantation state, as documented by repeated psychiatric reports and hospitalizations. To our knowledge, this is the first report of a patient who developed long-term PSEs that did not disappear after stimulation discontinuation. We suppose that ANT-DBS caused a persistent perturbation of the thalamic neuronal networks that are responsible for long-term PSEs.

Název v anglickém jazyce

Anterior thalamic deep brain stimulation in epilepsy and persistent psychiatric side effects following discontinuation

Popis výsledku anglicky

We report a case of a patient with drug-resistant epilepsy treated with deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS). The patient developed psychiatric side effects (PSEs), namely irritability, hostility, aggressiveness, and paranoia, after implantation and stimulation initiation. The stimulation was discontinued and the PSEs were mitigated, but the patient did not return to her pre-implantation state, as documented by repeated psychiatric reports and hospitalizations. To our knowledge, this is the first report of a patient who developed long-term PSEs that did not disappear after stimulation discontinuation. We suppose that ANT-DBS caused a persistent perturbation of the thalamic neuronal networks that are responsible for long-term PSEs.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

<a href="/cs/project/NV19-04-00343" target="_blank" >NV19-04-00343: Predikce Efektu Stimulace u pacientů s Epilepsií (PRESEnCE)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Epilepsy and Behavior Reports

ISSN

2589-9864

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

2019

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

3

Strana od-do

1-3

Kód UT WoS článku

000566534900006

EID výsledku v databázi Scopus

2-s2.0-85081058842