The role of intestinal microbiota in the pathogenesis of colorectal carcinoma

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F20%3A00115355" target="_blank" >RIV/00216224:14110/20:00115355 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/19:A20023L9 RIV/71009396:_____/20:N0000028 RIV/61988987:17110/20:A2202CXS

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s12223-019-00706-2" target="_blank" >http://dx.doi.org/10.1007/s12223-019-00706-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12223-019-00706-2" target="_blank" >10.1007/s12223-019-00706-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The role of intestinal microbiota in the pathogenesis of colorectal carcinoma

Popis výsledku v původním jazyce

The symbiotic relationship between intestinal microbiota and the host is a major mechanism of prevention against the development of chronic and metabolic diseases. The intestinal microbiota provides several physiological functions of the organism from the creation of a natural functional barrier with a subsequent immunostimulatory activity up to affecting the energy metabolism of the host. Disruption of physiological intestinal microbiota is reported as one of the major etiological factors of initiation and progression of colorectal carcinoma (CRC). Chronic low-grade inflammation is associated with the development of CRC, through the production of inflammatory cytokines and reactive oxygen species. CRC occurs in association with high-protein and high-fat diets in combination with low-fiber intake. The problem of intestinal dysbiosis and oncological diseases is a multidisciplinary problem and it is necessary to focus on several fields of medicine such as public health, clinical pharmacology, and internal medicine. The aim of this review is describing the role of gut dysbiosis in pathogenesis of colorectal carcinoma.

Název v anglickém jazyce

The role of intestinal microbiota in the pathogenesis of colorectal carcinoma

Popis výsledku anglicky

The symbiotic relationship between intestinal microbiota and the host is a major mechanism of prevention against the development of chronic and metabolic diseases. The intestinal microbiota provides several physiological functions of the organism from the creation of a natural functional barrier with a subsequent immunostimulatory activity up to affecting the energy metabolism of the host. Disruption of physiological intestinal microbiota is reported as one of the major etiological factors of initiation and progression of colorectal carcinoma (CRC). Chronic low-grade inflammation is associated with the development of CRC, through the production of inflammatory cytokines and reactive oxygen species. CRC occurs in association with high-protein and high-fat diets in combination with low-fiber intake. The problem of intestinal dysbiosis and oncological diseases is a multidisciplinary problem and it is necessary to focus on several fields of medicine such as public health, clinical pharmacology, and internal medicine. The aim of this review is describing the role of gut dysbiosis in pathogenesis of colorectal carcinoma.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Folia microbiologica

ISSN

0015-5632

e-ISSN

1874-9356

Svazek periodika

65

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

17-24

Kód UT WoS článku

000511921000002

EID výsledku v databázi Scopus

2-s2.0-85064595887