The role of intestinal microbiota in the pathogenesis of colorectal carcinoma
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F20%3AA2202CXS" target="_blank" >RIV/61988987:17110/20:A2202CXS - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61988987:17110/19:A20023L9 RIV/00216224:14110/20:00115355 RIV/71009396:_____/20:N0000028
Výsledek na webu
<a href="https://link.springer.com/article/10.1007/s12223-019-00706-2?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot" target="_blank" >https://link.springer.com/article/10.1007/s12223-019-00706-2?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12223-019-00706-2" target="_blank" >10.1007/s12223-019-00706-2</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The role of intestinal microbiota in the pathogenesis of colorectal carcinoma
Popis výsledku v původním jazyce
The symbiotic relationship between intestinal microbiota and the host is a major mechanism of prevention against the development of chronic and metabolic diseases. The intestinal microbiota provides several physiological functions of the organism from the creation of a natural functional barrier with a subsequent immunostimulatory activity up to affecting the energy metabolism of the host. Disruption of physiological intestinal microbiota is reported as one of the major etiological factors of initiation and progression of colorectal carcinoma (CRC). Chronic low-grade inflammation is associated with the development of CRC, through the production of inflammatory cytokines and reactive oxygen species. CRC occurs in association with high-protein and high-fat diets in combination with low-fiber intake. The problem of intestinal dysbiosis and oncological diseases is a multidisciplinary problem and it is necessary to focus on several fields of medicine such as public health, clinical pharmacology, and internal medicine. The aim of this review is describing the role of gut dysbiosis in pathogenesis of colorectal carcinoma. © 2019, Institute of Microbiology, Academy of Sciences of the Czech Republic, v.v.i.
Název v anglickém jazyce
The role of intestinal microbiota in the pathogenesis of colorectal carcinoma
Popis výsledku anglicky
The symbiotic relationship between intestinal microbiota and the host is a major mechanism of prevention against the development of chronic and metabolic diseases. The intestinal microbiota provides several physiological functions of the organism from the creation of a natural functional barrier with a subsequent immunostimulatory activity up to affecting the energy metabolism of the host. Disruption of physiological intestinal microbiota is reported as one of the major etiological factors of initiation and progression of colorectal carcinoma (CRC). Chronic low-grade inflammation is associated with the development of CRC, through the production of inflammatory cytokines and reactive oxygen species. CRC occurs in association with high-protein and high-fat diets in combination with low-fiber intake. The problem of intestinal dysbiosis and oncological diseases is a multidisciplinary problem and it is necessary to focus on several fields of medicine such as public health, clinical pharmacology, and internal medicine. The aim of this review is describing the role of gut dysbiosis in pathogenesis of colorectal carcinoma. © 2019, Institute of Microbiology, Academy of Sciences of the Czech Republic, v.v.i.
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
10609 - Biochemical research methods
Návaznosti výsledku
Projekt
—
Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Folia Microbiologica
ISSN
0015-5632
e-ISSN
—
Svazek periodika
65
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
8
Strana od-do
17-24
Kód UT WoS článku
—
EID výsledku v databázi Scopus
2-s2.0-85064595887