The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F20%3A00117549" target="_blank" >RIV/00216224:14110/20:00117549 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/20:00073673

Výsledek na webu

<a href="https://www.hindawi.com/journals/omcl/2020/8877116/" target="_blank" >https://www.hindawi.com/journals/omcl/2020/8877116/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2020/8877116" target="_blank" >10.1155/2020/8877116</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage

Popis výsledku v původním jazyce

This review focuses on the problem of oxidative stress in early brain injury (EBI) after spontaneous subarachnoid hemorrhage (SAH). EBI involves complex pathophysiological mechanisms, including oxidative stress. In the first section, we describe the main sources of free radicals in EBI. There are several sources of excessive generation of free radicals from mitochondrial free radicals' generation and endoplasmic reticulum stress, to hemoglobin and enzymatic free radicals' generation. The second part focuses on the disruption of antioxidant mechanisms in EBI. The third section describes some newly found molecular mechanisms and pathway involved in oxidative stress after EBI. The last section is dedicated to the pathophysiological mechanisms through which free radicals mediate early brain injury.

Název v anglickém jazyce

The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage

Popis výsledku anglicky

This review focuses on the problem of oxidative stress in early brain injury (EBI) after spontaneous subarachnoid hemorrhage (SAH). EBI involves complex pathophysiological mechanisms, including oxidative stress. In the first section, we describe the main sources of free radicals in EBI. There are several sources of excessive generation of free radicals from mitochondrial free radicals' generation and endoplasmic reticulum stress, to hemoglobin and enzymatic free radicals' generation. The second part focuses on the disruption of antioxidant mechanisms in EBI. The third section describes some newly found molecular mechanisms and pathway involved in oxidative stress after EBI. The last section is dedicated to the pathophysiological mechanisms through which free radicals mediate early brain injury.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10601 - Cell biology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Oxidative Medicine and Cellular Longevity

ISSN

1942-0900

e-ISSN

1942-0994

Svazek periodika

2020

Číslo periodika v rámci svazku

NOV 2020

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

1-9

Kód UT WoS článku

000596448900001

EID výsledku v databázi Scopus

2-s2.0-85097239748